Risk factors for borderline personality disorder in treatment seeking patients with a substance use disorder: An international multicenter study
Eur Addict Res. 2015-04-01; 21(4): 188-194
DOI: 10.1159/000371724
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1. Eur Addict Res. 2015;21(4):188-94. doi: 10.1159/000371724. Epub 2015 Apr 1.
Risk Factors for Borderline Personality Disorder in Treatment Seeking Patients
with a Substance Use Disorder: An International Multicenter Study.
Wapp M(1), van de Glind G, van Emmerik-van Oortmerssen K, Dom G, Verspreet S,
Carpentier PJ, Ramos-Quiroga JA, Skutle A, Bu ET, Franck J, Konstenius M, Kaye S,
Demetrovics Z, Barta C, Fatséas M, Auriacombe M, Johnson B, Faraone SV, Levin FR,
Allsop S, Carruthers S, Schoevers RA, Koeter MW, van den Brink W, Moggi F; IASP
Research Group.
Author information:
(1)University Hospital of Psychiatry, University of Bern, Bern, Switzerland.
Borderline personality disorder (BPD) and substance use disorders (SUDs) often
co-occur, partly because they share risk factors. In this international
multicenter study, risk factors for BPD were examined for SUD patients. In total,
1,205 patients were comprehensively examined by standardized interviews and
questionnaires on psychiatric diagnosis and risk factors, and it was found that
1,033 (85.7%) had SUDs without BPD (SUD) and 172 (14.3%) had SUD with BPD (SUD +
BPD). SUD + BPD patients were significantly younger, more often females and more
often diagnosed with comorbid adult attention deficit/hyperactivity disorder. SUD
+ BPD patients did not differ from SUD patients on most risk factors typical for
SUD such as maternal use of drugs during pregnancy or parents having any SUD.
However, SUD + BPD patients did have a higher risk of having experienced
emotional and physical abuse, neglect, or family violence in childhood compared
to SUD patients, suggesting that child abuse and family violence are BPD-specific
risk factors in patients with SUDs.
DOI: 10.1159/000371724
PMCID: PMC4869722
PMID: 25832736 [Indexed for MEDLINE]