Quality of life after Roux-en-Y gastric bypass and changes in body mass index and obesity-related comorbidities.
Diabetes & Metabolism. 2013-04-01; 39(2): 148-154
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1. Diabetes Metab. 2013 Apr;39(2):148-54. doi: 10.1016/j.diabet.2012.10.008. Epub
2013 Jan 10.
Quality of life after Roux-en-Y gastric bypass and changes in body mass index and
Julia C(1), Ciangura C, Capuron L, Bouillot JL, Basdevant A, Poitou C, Oppert JM.
(1)Department of Nutrition, Pitié-Salpêtrière Hospital (AP-HP), University
Pierre-et-Marie-Curie-Paris 6, Human Nutrition Research Center Île-de-France
(CRNH IdF), 83, boulevard de l’Hôpital, 75013 Paris, France.
AIM: Dynamics of improvement in health-related quality of life (QoL) after
bariatric surgery have never been fully assessed, and neither has the potential
influence of body mass index (BMI) and comorbidity modification. The objective of
this study was to investigate early and medium-term changes in QoL following
Roux-en-Y gastric bypass (RYGB), and their relationship to BMI and comorbidity
METHODS: A total of 71 obese subjects (80% women, mean age 42.1±11.2 years, mean
baseline BMI 47.6±6.2kg/m(2)) undergoing RYGB filled in QoL questionnaires
(SF-36) before and 3, 6 and 12 months after surgery. QoL was assessed using
repeated-measures Anova, with associations between its changes and changes in BMI
and comorbidities (diabetes, hypertension, dyslipidaemia, sleep apnoea, knee
pain) assessed by mixed-effects models.
RESULTS: Physical QoL scales (physical component summary, PCS) significantly
increased over time (from 38.9±9.3 to 52.6±7.9; P