Postembryonic development of corazonin-containing neurons and neurosecretory cells in the blowfly, Phormia terraenovae
J. Comp. Neurol.. 1994-12-22; 350(4): 559-572
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1. J Comp Neurol. 1994 Dec 22;350(4):559-72.
Postembryonic development of corazonin-containing neurons and neurosecretory
cells in the blowfly, Phormia terraenovae.
Cantera R(1), Veenstra JA, Nässel DR.
(1)Department of Zoology, Stockholm University, Sweden.
An antiserum against the cockroach cardioactive peptide corazonin was used to
investigate the distribution of immunoreactive neurons and neurosecretory cells
in the nervous system of the blowfly, Phormia terraenovae, during postembryonic
development. A small number of corazonin-immunoreactive neurons was found at
larval, pupal, and adult stages. At all postembryonic stages two cell groups were
found in the protocerebrum of the brain: 1) two lateral cell clusters and 2) two
median cells. In the larva eight bilateral cell pairs were found in thoracic and
abdominal neuromeres of the fused ventral ganglion. The lateral brain neurons are
located in the lateral neurosecretory cell group and extend axons with branches
in several components of the retrocerebral neuroendocrine complex, in the
stomatogastric nervous system of larvae and adults, and additionally in muscles
of the alimentary canal in the adult. The most prominent element of these
peripheral processes is a large plexus of varicose fibers located in the wall of
the aorta, the main site for the release of neurohormones produced in the brain
of blowflies. The presence of corazonin-immunoreactive material in the aortic
plexus suggests that this peptide functions as a neurohormone. During
metamorphosis, the immunoreactive neurons found in the thoracic-abdominal
ganglion of the larva disappear, and in the brain new immunoreactive neurons are
added to those that persist from larval stages. The bulk of the
corazonin-immunoreactive material extracted from adult brains and corpora
cardiaca-aorta complexes was found to co-elute with synthetic corazonin in
reversed-phase high-performance liquid chromatography as monitored with
enzyme-linked immunosorbent assay.
PMID: 7890830 [Indexed for MEDLINE]