PHYSICAL EXERCISE AND BRAIN MONOAMINES – A REVIEW
Acta Physiologica Scandinavica. 1989-09-01; 137(1): 1-13
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1. Acta Physiol Scand. 1989 Sep;137(1):1-13.
Physical exercise and brain monoamines: a review.
(1)Department of Pharmacology, INSERM U7, Paris, France.
A review of the literature on the relationship of exercise to mental health
strongly suggests that the two are closely linked. Thus, physical activity has
been reported to reduce depression symptoms and anxiety, and to improve coping
with stress. Logically, many investigators have then tried to determine the
physiological mechanisms that are responsible for this mood-elevating effect of
exercise. Among the current hypotheses, those regarding the endorphin and the
monoamine systems have received a great deal of attention. On that basis, the
respective effects of physical exercise on brain dopamine, noradrenaline and
serotonin transmission are reviewed herein. In addition, suggestions are advanced
for future research in this field.
PMID: 2678895 [Indexed for MEDLINE]