Perceptual abnormalities related to sensory gating deficit are core symptoms in adults with ADHD
Psychiatry Research. 2015-12-01; 230(2): 357-363
DOI: 10.1016/j.psychres.2015.09.016
Lire sur PubMed
1. Psychiatry Res. 2015 Dec 15;230(2):357-63. doi: 10.1016/j.psychres.2015.09.016.
Epub 2015 Sep 13.
Perceptual abnormalities related to sensory gating deficit are core symptoms in
adults with ADHD.
Micoulaud-Franchi JA(1), Lopez R(2), Vaillant F(3), Richieri R(4), El-Kaim A(3),
Bioulac S(5), Philip P(6), Boyer L(4), Lancon C(4).
Author information:
(1)Bordeaux Sleep Clinique, Pellegrin University Hospital, 33076 Bordeaux,
France; Bordeaux University, USR CNRS 3413 SANPSY, Research Unit, 33000 Bordeaux,
France. Electronic address: .
(2)Department of Neurology and Sleep Medicine, Gui-de-Chauliac University
Hospital, 34000 Montpellier, France; Inserm U1061, Research Unit, 34000
Montpellier, France.
(3)Department of Psychiatry, Sainte-Marguerite University Hospital, 13009
Marseille, France.
(4)Department of Psychiatry, Sainte-Marguerite University Hospital, 13009
Marseille, France; Aix-Marseille University, EA 3279, Public Health, Chronic
Diseases and Quality of Life, Research Unit, 13005 Marseille, France.
(5)Bordeaux Sleep Clinique, Pellegrin University Hospital, 33076 Bordeaux,
France; Bordeaux University, USR CNRS 3413 SANPSY, Research Unit, 33000 Bordeaux,
France; Department of Children Psychiatry, Charles Perrens Hospital, 33000
Bordeaux, France.
(6)Bordeaux Sleep Clinique, Pellegrin University Hospital, 33076 Bordeaux,
France; Bordeaux University, USR CNRS 3413 SANPSY, Research Unit, 33000 Bordeaux,
France.
This study investigated and compared perceptual abnormalities related to sensory
gating deficit in adult patients with Attention Deficit Disorder with
Hyperactivity (A-ADHD) and adult patients with schizophrenia. Subjects were
evaluated with the Sensory Gating Inventory (SGI). We compared SGI scores between
patients with A-ADHD, patients with schizophrenia and healthy subjects. We also
assessed the relationship between SGI scores and clinical symptoms, and evaluated
the ability of the SGI to detect perceptual abnormalities in A-ADHD. Seventy
adult patients with ADHD reported higher SGI scores than the 70 healthy subjects
and the 70 patients with schizophrenia. The inattention factor of the ASRS
correlated significantly with the overall SGI score. The ROC AUC for the overall
SGI score in the A-ADHD group (versus the healthy group) illustrated good
performance. The findings suggest that i) perceptual abnormalities are core
symptoms of adult patients with ADHD and ii) the attention of patients with
A-ADHD may be involuntarily drowned by many irrelevant environmental stimuli
leading to their impaired attention on relevant stimuli. They also confirm that
the SGI could be a useful self-report instrument to diagnose the clinical
features of A-ADHD.
Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.
DOI: 10.1016/j.psychres.2015.09.016
PMID: 26416589 [Indexed for MEDLINE]