Novel self-replicating α-synuclein polymorphs that escape ThT monitoring can spontaneously emerge and acutely spread in neurons.

Francesca De Giorgi, Florent Laferrière, Federica Zinghirino, Emilie Faggiani, Alons Lends, Mathilde Bertoni, Xuan Yu, Axelle Grélard, Estelle Morvan, Birgit Habenstein, Nathalie Dutheil, Evelyne Doudnikoff, Jonathan Daniel, Stéphane Claverol, Chuan Qin, Antoine Loquet, Erwan Bezard, François Ichas
Sci. Adv.. 2020-10-02; 6(40):
DOI: 10.1126/sciadv.abc4364

https://www.bordeaux-neurocampus.fr/11996

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