Neuroscience: Direct evidence for a parietal-frontal pathway subserving spatial awareness in humans

M. T. de Schotten
Science. 2005-09-30; 309(5744): 2226-2228
DOI: 10.1126/science.1116251

PubMed
Lire sur PubMed



1. Science. 2005 Sep 30;309(5744):2226-8.

Direct evidence for a parietal-frontal pathway subserving spatial awareness in
humans.

Thiebaut de Schotten M(1), Urbanski M, Duffau H, Volle E, Lévy R, Dubois B,
Bartolomeo P.

Author information:
(1)INSERM Unit 610, Assistance Publique-Hôpitaux de Paris, Hôpital de la
Salpêtrière, 75013 Paris, France.

Erratum in
Science. 2007 Aug 3;317(5838):597.

Comment in
Science. 2005 Sep 30;309(5744):2172-3.

Intraoperative electrical stimulation, which temporarily inactivates restricted
regions during brain surgery, can map cognitive functions in humans with
spatiotemporal resolution unmatched by other methods. Using this technique, we
found that stimulation of the right inferior parietal lobule or the caudal
superior temporal gyrus, but not of its rostral portion, determined rightward
deviations on line bisection. However, the strongest shifts occurred with
subcortical stimulation. Fiber tracking identified the stimulated site as a
section of the superior occipitofrontal fasciculus, a poorly known
parietal-frontal pathway. These findings suggest that parietal-frontal
communication is necessary for the symmetrical processing of the visual scene.

DOI: 10.1126/science.1116251
PMID: 16195465 [Indexed for MEDLINE]

Auteurs Bordeaux Neurocampus