Multiprotein Printing by Light-Induced Molecular Adsorption

Pierre-Olivier Strale, Ammar Azioune, Ghislain Bugnicourt, Yohan Lecomte, Makhlad Chahid, Vincent Studer
Adv Mater. 2016-03; 28(10): 2024-9
DOI: 10.1002/adma.201504154

Light-induced molecular adsorption of proteins (LIMAP) allows for quantitative sub-micrometer-resolution printing of multiple biomolecules. Surface-bound gradients are patterned within minutes over an entire glass cover-slip. LIMAP is used to perform selective immuno-assays, to dynamically control the adhesion of individual cells, and to achieve hierarchical co-cultures instrumental for tissue engineering.

Keywords: cell co-culture; photopatterning; poly(ethylene glycol); protein micropatterning; single molecules.

Auteurs Bordeaux Neurocampus