Long-term chronic diseases and crash responsibility: A record linkage study

Ludivine Orriols, Marta Avalos-Fernandez, Nicholas Moore, Pierre Philip, Bernard Delorme, Bernard Laumon, Blandine Gadegbeku, Louis-Rachid Salmi, Emmanuel Lagarde
Accident Analysis & Prevention. 2014-10-01; 71: 137-143
DOI: 10.1016/j.aap.2014.05.001

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1. Accid Anal Prev. 2014 Oct;71:137-43. doi: 10.1016/j.aap.2014.05.001. Epub 2014
Jun 12.

Long-term chronic diseases and crash responsibility: a record linkage study.

Orriols L(1), Avalos-Fernandez M(2), Moore N(3), Philip P(4), Delorme B(5),
Laumon B(6), Gadegbeku B(6), Salmi LR(7), Lagarde E(8).

Author information:
(1)Univ. Bordeaux, ISPED, Centre INSERM U897-Epidemiologie-Biostatistique,
F-33000 Bordeaux, France; INSERM, Equipe Prévention et prise en charge des
traumatismes, ISPED, Centre INSERM U897-Epidemiologie-Biostatistique, F-33000
Bordeaux, France. Electronic address: .
(2)Univ. Bordeaux, ISPED, Centre INSERM U897-Epidemiologie-Biostatistique,
F-33000 Bordeaux, France; INSERM, Equipe Biostatistique, ISPED, Centre INSERM
U897-Epidemiologie-Biostatistique, F-33000 Bordeaux, France.
(3)INSERM U657, CIC-P0005, Département de Pharmacologie, Université Bordeaux
Segalen, Bordeaux, France.
(4)USR CNRS SANPSY 3413, Université Bordeaux Segalen, Bordeaux, France.
(5)Pôle information des professionnels et du public, Direction de la
communication et de l’information, Agence nationale de sécurité du médicament et
des produits de santé (ANSM), Saint-Denis, France.
(6)Université de Lyon, F-69000 Lyon, France; IFSTTAR, UMR T 9405, UMRESTTE,
F-69500 Bron, France; Université Lyon 1, UMRESTTE, F-69000 Lyon, France.
(7)Univ. Bordeaux, ISPED, Centre INSERM U897-Epidemiologie-Biostatistique,
F-33000 Bordeaux, France; INSERM, Equipe Prévention et prise en charge des
traumatismes, ISPED, Centre INSERM U897-Epidemiologie-Biostatistique, F-33000
Bordeaux, France; Service d’information médicale, CHU de Bordeaux, France.
(8)Univ. Bordeaux, ISPED, Centre INSERM U897-Epidemiologie-Biostatistique,
F-33000 Bordeaux, France; INSERM, Equipe Prévention et prise en charge des
traumatismes, ISPED, Centre INSERM U897-Epidemiologie-Biostatistique, F-33000
Bordeaux, France.

OBJECTIVE: To assess the population impact of chronic conditions on the risk of
road traffic crashes.
METHODS: Data from three French national databases were extracted and matched:
the national health care insurance database, police reports and the national
police database of injurious crashes. Exposure to chronic conditions were
compared between responsible and nonresponsible drivers. Analysis was performed
using the Lasso (least absolute shrinkage and selection operator) method.
RESULTS: 69,630 drivers involved in an injurious crash in France between 2005 and
2008, were included. 6210 (8.9%) were suffering from at least one long-term
disease. When adjusted for prescription of medicines, blood alcohol, demographic
driver characteristics and crash characteristics, increased risk of being
responsible for a crash was found in drivers registered in the French healthcare
database with the following long-term diseases: epilepsy (odds ratio [OR]=2.53
[1.53-4.20]), type 1 diabetes (OR=1.47) [1.12-1.92], alcoholic liver disease
(OR=3.37 [1.40-8.13]), asthma (OR=1.72 [1.13-2.60]) and specific personality
disorders (OR=1.35 [1.05-1.74]). No association was found for cardiovascular
diseases or Alzheimer’s disease.
CONCLUSION: The results update the list of medical conditions that may impair
driving skills. However, results should be considered cautiously with regards to
potential regulatory driving judgments that could have a negative impact on
patients’ social life.

Copyright © 2014 Elsevier Ltd. All rights reserved.

DOI: 10.1016/j.aap.2014.05.001
PMID: 24929821 [Indexed for MEDLINE]

Auteurs Bordeaux Neurocampus