Isolation of a novel RFamide peptide from the midgut of the American cockroach, Periplaneta americana
Biochemical and Biophysical Research Communications. 1995-08-01; 213(2): 519-524
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1. Biochem Biophys Res Commun. 1995 Aug 15;213(2):519-24.
Isolation of a novel RFamide peptide from the midgut of the American cockroach,
Veenstra JA(1), Lambrou G.
(1)Department of Entomology, University of Arizona, Tucson 85721, USA.
In insects (FM)RFamide-immunoreactive endocrine cells are ubiquitously present in
the midgut, but the identity of the peptide(s) produced by these cells is
unknown. The major RFamide-immunoreactive peptide from the midgut of the American
cockroach, Periplaneta americana, was isolated and identified as
Ala-Asn-Arg-Ser-Leu-Arg-Leu-Arg-Pheamide. This is a novel member of an arthropod
peptide family, previously known only from mosquitoes and horseshoe crabs. Its
abundance in the midgut suggests that it plays an important function in
PMID: 7646507 [Indexed for MEDLINE]