Intraoperative Neurophysiological Evidence of Hydrogen Peroxide-Induced Stroke in Insular Tumor Surgery.

Alba Leon Jorba, Miguel Lopez Cuina, Gloria Villalba Martinez, Alessandro Principe
Turkish Neurosurgery. 2014-01-01; :
DOI: 10.5137/1019-5149.jtn.11387-14.1

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1. Turk Neurosurg. 2015;25(4):674-7. doi: 10.5137/1019-5149.JTN.11387-14.1.

Intraoperative Neurophysiological Evidence of Hydrogen Peroxide-Induced Stroke in
Insular Tumor Surgery.

León Jorba A(1), López Cuiña M, Principe A, Villalba Martínez G.

Author information:
(1)Parc de Salut Mar, Department of Neurology, Barcelona, Spain.

Hydrogen peroxide (H2O2) is commonly used as a haemostatic agent in all type of
surgeries. Some adverse effects have been described related to its use. However,
only very few cases are published in the literature of a stroke associated with
the application of this agent directly to the brain. We present the case of a
patient operated on for a right insular tumor with the assistance of
intraoperative neurophysiological monitoring who developed a postoperative severe
hemiparesis caused by a stroke in left middle cerebral artery territory due to
the irrigation with H2O2. Based on this case, we recommend avoiding the H2O2
irrigation for hemostasis in surgery for brain tumors when vascular structures
are exposed.

DOI: 10.5137/1019-5149.JTN.11387-14.1
PMID: 26242351 [Indexed for MEDLINE]


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