Hippocampal Neurons: Simulating the Spatial Structure of a Complex Maze
Current Biology. 2014-07-01; 24(14): R643-R645
DOI: 10.1016/j.cub.2014.06.001
1. Curr Biol. 2014 Jul 21;24(14):R643-R645. doi: 10.1016/j.cub.2014.06.001.
Hippocampal neurons: simulating the spatial structure of a complex maze.
Jeffery K(1), Casali G(2).
Author information:
(1)Institute of Behavioural Neuroscience, Department of Experimental Psychology,
Division of Psychology and Language Sciences, University College London, London
WC1H 0AP, UK. Electronic address: .
(2)Institute of Behavioural Neuroscience, Department of Experimental Psychology,
Division of Psychology and Language Sciences, University College London, London
WC1H 0AP, UK.
Comment on
J Neurosci. 2014 May 7;34(19):6459-69. doi: 10.1523/JNEUROSCI.3414-13.2014.
Hippocampal place neurons not only represent current location, but fire in
sequences that appear to simulate past and future spatial trajectories. A recent
study has found that the firing sequences match the structure of a complex maze,
suggesting that the structure of the environment is encoded by the place system,
perhaps to aid navigational planning.
Copyright © 2014 Elsevier Ltd. All rights reserved.
DOI: 10.1016/j.cub.2014.06.001
PMID: 25050959 [Indexed for MEDLINE]