[Grading of adults primitive glial neoplasms using arterial spin-labeled perfusion MR imaging].

S. Canale, S. Rodrigo, T. Tourdias, C. Mellerio, M. Perrin, R. Souillard, C. Oppenheim, J.F. Meder
Journal of Neuroradiology. 2011-10-01; 38(4): 207-213
DOI: 10.1016/j.neurad.2010.12.003

PubMed
Lire sur PubMed



1. J Neuroradiol. 2011 Oct;38(4):207-13. doi: 10.1016/j.neurad.2010.12.003. Epub
2011 Feb 25.

[Grading of adults primitive glial neoplasms using arterial spin-labeled
perfusion MR imaging].

[Article in French]

Canale S(1), Rodrigo S, Tourdias T, Mellerio C, Perrin M, Souillard R, Oppenheim
C, Meder JF.

Author information:
(1)Service de neuroradiologie, centre hospitalier Sainte-Anne, université Paris
Descartes, 1, rue Cabanis, 75014 Paris, France.

PURPOSE: We investigated the relationship between tumor blood-flow measurement
based on perfusion-imaging by arterial spin-labeling (ASL) and histopathologic
findings in adults’ primitive glial tumours.
PATIENTS AND METHODS: Thus, 40 primitive brain tumors (8 low-grade and 32
high-grade gliomas according to the Sainte-Anne classification) were imaged using
pulsed (n=19) or continuous (n=21) ASL. Relative cerebral blood flow
(rCBF=tumoral blood flow/normal cerebral blood flow) between high- and low-grade
gliomas were compared.
RESULTS: Using pulsed ASL, differences in mean rCBF were observed in high- and
low-grade gliomas although no significant (respectively 1.95 and 1.5). Using
continuous ASL, mean rCBF were significantly higher for high-grade than for
low-grade gliomas (P

Auteurs Bordeaux Neurocampus