Experience in the clinical and genetic diagnosis of a series of Algerian patients with hereditary spastic paraplegias

Mouna Messaoud-Khelifi, Razika Boulariah-Hadjou, Mohamed Islam Kediha, Lena Guillot-Noel, Marine Guillaud-Bataille, Christelle Marie Durand, Lamia Ali-Pacha, Wahiba Amer El Khedoud, Fanny Mochel, Jean-Madeleine de Sainte-Agathe, Giovanni Stevanin
Neurogenetics. 2025-06-25; 26(1):
DOI: 10.1007/s10048-025-00833-8

1. Neurogenetics. 2025 Jun 25;26(1):52. doi: 10.1007/s10048-025-00833-8.

Experience in the clinical and genetic diagnosis of a series of Algerian
patients with hereditary spastic paraplegias.

Messaoud-Khelifi M(1), Boulariah-Hadjou R(#)(2), Kediha MI(#)(3), Guillot-Noel
L(4), Guillaud-Bataille M(5), Durand CM(6), Ali-Pacha L(#)(3), Amer El Khedoud
W(#)(2), Mochel F(4)(5), de Sainte-Agathe JM(5), Stevanin G(7)(8).

Author information:
(1)Laboratoire de Biologie Cellulaire et Moléculaire, Faculté des Sciences
Biologiques, Université des Sciences et de la Technologie Houari Boumediene
(USTHB), Alger, Algérie. .
(2)Service de Neurologie, EHS de Ben Aknoun, Alger, Algérie.
(3)Service de Neurologie, CHU Mustapha Pacha, Alger, Algérie.
(4)Sorbonne Université, Paris Brain Institute- ICM, INSERM, CNRS, AP-HP, Paris,
France.
(5)DMU BioGeM, Département de Génétique Médicale, Assistance Publique Hôpitaux
de Paris-Sorbonne Université, Paris, France.
(6)Incia, Bordeaux university, CNRS, UMR5287, Bordeaux, France.
(7)Incia, Bordeaux university, CNRS, UMR5287, Bordeaux, France.
.
(8)PSL Research University, EPHE, Paris, France. .
(#)Contributed equally

DOI: 10.1007/s10048-025-00833-8
PMID: 40560206

Conflict of interest statement: Declarations. Ethics approval: All procedures
performed in human participants were done in accordance with the ethical
agreement of the Mustapha Hospital ethics committee (n° 17/CE/2025) and followed
the 1964 Helsinki Declaration and its later amendments. Consent to participate:
Informed written consent from all human subjects or their legal guardians, have
been obtained prior to clinical examination and blood sampling, allowing the
genetic testing and use of the data for scientific publication. Informed
consent: Informed written consent from all human subjects or their legal
guardians, have been obtained prior to clinical examination and blood sampling,
allowing the genetic testing and use of the data for scientific publication.
Competing interests: GS received a grant from Biogen, unrelated to this study
from 2019 to 2023. All other authors have no relevant financial or non-financial
interests to disclose.