Efficacy and compliance of mandibular repositioning device in obstructive sleep apnea syndrome under a patient-driven protocol of care
Sleep Medicine. 2008-10-01; 9(7): 762-769
DOI: 10.1016/j.sleep.2007.09.007
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1. Sleep Med. 2008 Oct;9(7):762-9. Epub 2007 Nov 5.
Efficacy and compliance of mandibular repositioning device in obstructive sleep
apnea syndrome under a patient-driven protocol of care.
Vecchierini MF(1), Léger D, Laaban JP, Putterman G, Figueredo M, Levy J, Vacher
C, Monteyrol PJ, Philip P.
Author information:
(1)CHU Bichat-Claude Bernard, APHP, Paris, France.
OBJECTIVE: To assess the efficacy and compliance of a traction-based mandibular
repositioning device (MRD) for treatment of moderate to severe obstructive sleep
apnea syndrome (OSAS) under a patient-driven protocol in a routine outpatient
care setting.
METHODS: Forty patients, 10 severe and 30 moderate OSAS sufferers (apnea-hypopnea
index [AHI] >30 and between 15 and 30, respectively), were enrolled by four sleep
centers. Nocturnal polygraphy, quality of life, and quality of sleep
questionnaires were used to measure the effect of treatment after 45 days.
RESULTS: Thirty-five patients completed the study. Frequency of respiratory
events, daytime sleepiness, snoring, patient assessment of sleep quality,
specific short-form multipurpose health survey (SF-36) and the Pittsburgh Sleep
Quality Index (PSQI) improved significantly with the MRD. Sixty percent of
patients were « responders » (>50% decrease in AHI); 46% of patients were « full
responders » (>50% decrease and AHI