Differential Corticospinal Excitability and Cortical Functional Connectivity Modulation by Spinal Cord Transcutaneous Stimulation-based Motor Training versus Motor Training alone in Able-bodied and SCI participants: A Multiple Case Study
2023 45th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC). 2023-07-24; : 1-4
DOI: 10.1109/EMBC40787.2023.10340957
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1. Annu Int Conf IEEE Eng Med Biol Soc. 2023 Jul;2023:1-4. doi:
10.1109/EMBC40787.2023.10340957.
Differential Corticospinal Excitability and Cortical Functional Connectivity
Modulation by Spinal Cord Transcutaneous Stimulation-based Motor Training versus
Motor Training alone in Able-bodied and SCI participants: A Multiple Case Study.
Brihmat N, Bayram MB, Ravi M, Bheemreddy A, Anjaria M, Momeni K, Saleh S,
Forrest GF.
Spinal cord transcutaneous stimulation (scTS) has shown its potential for
boosting motor, sensory, and autonomic function recovery after a spinal cord
injury. Despite the demonstrated benefits, little is known about the exact
neuromodulatory mechanisms triggered by scTS and the cortex involvement in the
beneficial effects observed. Here, we examine the effects of scTS-based motor
training and motor training alone on sensorimotor cortical functional
connectivity and corticospinal excitability in able-bodied and SCI
participants.Clinical Relevance- The results show preliminary evidence of
differential cortical involvement and modulation by scTS-based motor training in
uninjured and spinal-cord injured individuals. A better understanding of scTS
mechanisms of action could help optimize the intervention design and potentiate
its benefits.
DOI: 10.1109/EMBC40787.2023.10340957
PMID: 38083293 [Indexed for MEDLINE]