Covid-19 Infection and Parkinsonism: Is There a Link?
Mov Disord. 2021-06-08; 36(8): 1737-1743
DOI: 10.1002/mds.28680
Lire sur PubMed
1. Mov Disord. 2021 Aug;36(8):1737-1743. doi: 10.1002/mds.28680. Epub 2021 Jun 8.
Covid-19 Infection and Parkinsonism: Is There a Link?
Bouali-Benazzouz R(1)(2), Benazzouz A(1)(2).
Author information:
(1)Université de Bordeaux, Institut des maladies neurodégénératives, Bordeaux,
France.
(2)CNRS, Institut des maladies neurodégénératives, Bordeaux, France.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an opportunistic
pathogen that infects the upper respiratory tract in humans and causes serious
illness, including fatal pneumonia and neurological disorders. Several studies
have reported that SARS-CoV-2 may worsen the symptoms of Parkinson’s disease
(PD), with the potential to increase mortality rates in patients with advanced
disease. The potential risk of SARS-CoV-2 to induce PD has also been suggested
because the virus can enter the brain, where it can trigger cellular processes
involved in neurodegeneration. In this review, we will discuss the potential of
SARS-CoV-2 to exacerbate and cause certain neurological disorders, including PD.
We will then elucidate its impact on the brain while examining its pathways and
mechanisms of action. © 2021 International Parkinson and Movement Disorder
Society.
© 2021 International Parkinson and Movement Disorder Society.
DOI: 10.1002/mds.28680
PMCID: PMC8242862
PMID: 34080714 [Indexed for MEDLINE]