BIL&GIN: A neuroimaging, cognitive, behavioral, and genetic database for the study of human brain lateralization.
NeuroImage. 2016-01-01; 124: 1225-1231
DOI: 10.1016/j.neuroimage.2015.02.071
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1. Neuroimage. 2016 Jan 1;124(Pt B):1225-31. doi: 10.1016/j.neuroimage.2015.02.071.
Epub 2015 Apr 1.
BIL&GIN: A neuroimaging, cognitive, behavioral, and genetic database for the
study of human brain lateralization.
Mazoyer B(1), Mellet E(2), Perchey G(2), Zago L(2), Crivello F(2), Jobard G(2),
Delcroix N(2), Vigneau M(2), Leroux G(2), Petit L(2), Joliot M(2),
Tzourio-Mazoyer N(2).
Author information:
(1)CNRS UMR5296 Groupe d’Imagerie Neurofonctionnelle, Bordeaux, France; CEA
UMR5296 Groupe d’Imagerie Neurofonctionnelle, Bordeaux, France; Université de
Bordeaux, UMR5296 Groupe d’Imagerie Neurofonctionnelle, Bordeaux, France.
Electronic address: .
(2)CNRS UMR5296 Groupe d’Imagerie Neurofonctionnelle, Bordeaux, France; CEA
UMR5296 Groupe d’Imagerie Neurofonctionnelle, Bordeaux, France; Université de
Bordeaux, UMR5296 Groupe d’Imagerie Neurofonctionnelle, Bordeaux, France.
We report on a database, named BIL&GIN, designed for investigating the cognitive,
behavioral, genetic, and brain morphological/functional correlates of hemispheric
specialization. The database contains records from a sample of 453 adult
participants enriched in left-handers (45%, N=205) as compared to the general
population. For each subject, socio-demographic data, hand and eye laterality,
family handedness, and cognitive abilities in the language, motor, visuo-spatial,
and numerical domains have been recorded. T1-MRI and DTI data were also acquired,
as well as resting-state functional MRI. Task-evoked functional MRI was performed
in a sub-sample of 303 subjects (157 left-handers) using a customized functional
battery of 16 cognitive tasks exploring the same three cognitive domains.
Performances at the tasks executed in the magnet as well as post-acquisition
debriefing were recorded. A saliva sample was obtained from the subjects of this
sub-sample from which DNA was extracted. The BIL&GIN contains results of imaging
data processing for each subject, namely maps of tissue (GM, WM, CSF)
probability, cortical thickness, cortical surface, and diffusion parameters as
well as regional values of these phenotypes for regions of both AAL and
FreeSurfer parcellations. For the subjects who underwent FMRI, individual SPM
contrast maps for each of the 8 runs were also calculated and included in the
database, as well as corresponding BOLD variations in ROIs of the AAL and AICHA
atlases, and Wilke’s hemispheric functional lateralization index. The BIL&GIN
data sharing is based on a collaborative model.
Copyright © 2015 Elsevier Inc. All rights reserved.
DOI: 10.1016/j.neuroimage.2015.02.071
PMID: 25840118 [Indexed for MEDLINE]