A video Clinical Global Impression (CGI) in obsessive compulsive disorder.
Psychiatry Research. 2011-03-01; 186(1): 117-122
DOI: 10.1016/j.psychres.2010.06.021
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1. Psychiatry Res. 2011 Mar 30;186(1):117-22. doi:
10.1016/j.psychres.2010.06.021. Epub 2011 Feb 12.
A video Clinical Global Impression (CGI) in obsessive compulsive disorder.
Bourredjem A(1), Pelissolo A, Rotge JY, Jaafari N, Machefaux S, Quentin S, Bui
E, Bruno N, Pochon JB, Polosan M, Baup N, Papetti F, Chéreau I, Arbus C, Mallet
L, du Montcel ST; French « Stimulation dans le Trouble Obsessionnel Compulsif
(STOC) » Study Group.
Collaborators: Mallet L, Agid Y, Aouizerate B, Arbus C, Bougerol T, Damier P,
Fontaine D, Houeto JL, Krebs MO, Lemaire JJ, Mallet L, Millet B, Pollak P,
Hourton D, Aprelon S, Jourdain C, Bardinet E, Yelnik J, Burbaud P, Welter ML,
Clair AH, Czernecki V, Vérin M, du Montcel ST, Madar D, Mallet L, Pelissolo A,
du Montcel ST, Welter ML, Yelnik J, Mallet L, Pelissolo A, Agid Y, Cornu P,
Navarro S, Welter ML, Hartmann A, Pidoux B, Grabli D, Czernecki V, Dormont D,
Galanaud D, Yelnik J, Bardinet E, Béhar C, Worbe Y, Clair AH, Moutaud B,
Aouizerate B, Burbaud P, Cuny E, Guehl D, Llorca PM, Chéreau I, Lemaire JJ,
Durif F, Derost P, Coste J, Gabrillargues J, Barget M, de Chazeron I, Bougerol
T, Polosan M, Benabid AL, Chabardès S, Seigneuret E, Krack P, Pollak P, Ardouin
C, Le Bas JF, Damier P, Lajat Y, Raoul S, Mattei V, Fontaine D, Borg M, Paquis
P, Michel E, Robert P, Magnié-Mauro MN, Papetti F, Baup N, Devaux B, Krebs MO,
Oppenheimer C, Olié JP, Ranoux D, Chayet M, Houeto JL, Jaafari N, Bataille B,
Mesnage V, Gil R, Audouin V, Senon JL, Millet B, Vérin M, Drapier D, Sauleau P,
Drapier S, Arbus C, Lazorthe Y, Chaynes P, Fabre N, Simonetta M, Schmitt L,
Lotterie JA, Camassel C, Best N, Aussilloux JC, Blond S, Feingold J, Sicard D,
Adès J, Cottraux J, Goudemand M.
Author information:
(1)Pierre and Marie Curie Paris 6 University, ER4, Modelling in Clinical
Research, Paris, France.
The Clinical Global Impression scale (CGI) is frequently used in clinical
research because of its face validity and ease of use but data on its
reliability are scarce. Our goal was to estimate the reliability of the scale
and compare reliability between face-to-face and video scoring. We analyzed 50
different video interviews recorded during 5 visits of a crossover trial to
study the effect of subthalamic nucleus stimulation. Six specialized clinicians
rated the CGI using these videos, providing 300 different ratings. The
intraclass correlation was lower at inclusion (0.30 [0.13-0.50]) than at later
visits (0.68 [0.61-0.80]). Reliability was not influenced by the patients’
stimulation status. The mean of at least two independent evaluations of the
video is needed to achieve an ICC greater than 0.8. The video CGI is a valid
clinical outcome measure suitable for clinical trials (ClinicalTrials.gov
number, NCT00169377).
Copyright © 2010 Elsevier Ltd. All rights reserved.
DOI: 10.1016/j.psychres.2010.06.021
PMID: 20621362 [Indexed for MEDLINE]