Harnessing a snake metabolite to control food intake

Adèle Buckenmeyer, Nabil Nasri, Daniela Cota
Trends in Endocrinology & Metabolism. 2026-05-01; :
DOI: 10.1016/j.tem.2026.04.013

Buckenmeyer A(1), Nasri N(1), Cota D(2).

Author information:
(1)University of Bordeaux, INSERM, Neurocentre Magendie, U1215, Bordeaux
F-33000, France.
(2)University of Bordeaux, INSERM, Neurocentre Magendie, U1215, Bordeaux
F-33000, France. Electronic address: .

Many diverse signals regulate feeding behavior. In Nature Metabolism, Xiao et
al. describe the discovery of a new appetite-suppressant metabolite found in
pythons, which is also conserved in humans. This research broadens our
understanding of postprandial physiology and raises new questions related to
metabolic pathology and therapy.

DOI: 10.1016/j.tem.2026.04.013
PMID: 42135173

Conflict of interest statement: Declaration of interests The authors declare no
competing interests.