Podcast: Giovanni Marsicano in « Mind & Matter »

Giovanni Marsicano (Neurocentre Magendie) has been invited by the podcast « Mind & Matter » to discuss the endocannabinoid system, starting with its core components like CB1 receptors and lipid-based molecules such as anandamide and 2-AG, derived from omega-6 fatty acids. He explains its cellular signaling, evolutionary role in energy storage for uncertain futures (exostasis vs. endostasis), and effects across tissues like the liver, gut, and brain, including motivation, appetite, pain relief, and anxiety regulation, while touching on biphasic effects of cannabinoids.