Protocol for extracellular recordings in the external globus pallidus of the behaving/awake monkey
STAR Protocols. 2024-06-01; 5(2): 103081
DOI: 10.1016/j.xpro.2024.103081
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https://www.bordeaux-neurocampus.fr/11942
Katabi S(1), Israel Z(2), Bergman H(3), Deffains M(4).
Author information:
(1)Department of Medical Neuroscience, Institute of Medical Research
Israel-Canada (IMRIC), The Hebrew University-Hadassah Medical School, Jerusalem
91120, Israel. Electronic address: .
(2)Department of Neurosurgery, Hadassah Medical Center, Jerusalem 91120, Israel.
(3)Department of Medical Neuroscience, Institute of Medical Research
Israel-Canada (IMRIC), The Hebrew University-Hadassah Medical School, Jerusalem
91120, Israel; Department of Neurosurgery, Hadassah Medical Center, Jerusalem
91120, Israel; The Edmond and Lily Safra Center for Brain Sciences, The Hebrew
University, Jerusalem 91904, Israel.
(4)University of Bordeaux, UMR 5293, IMN, 33000 Bordeaux, France; CNRS, UMR
5293, IMN, 33000 Bordeaux, France. Electronic address:
.
Extracellular recordings in behaving animals are useful for establishing
associations between neuronal activity and behavior. Here, we describe how to
record in the external globus pallidus (GPe) of monkeys engaged in a behavioral
task. We detail the stereotaxic surgery for chamber and head-holder
implantation, the post-operative MRI scan to ascertain the GPe coordinates and
validate the position of the chamber, and the data collection. This protocol
makes it possible to examine the electrophysiological features of GPe neurons in
behaving monkeys. For complete details on the use and execution of this
protocol, please refer to Katabi et al.1.
Copyright © 2024 The Authors. Published by Elsevier Inc. All rights reserved.
DOI: 10.1016/j.xpro.2024.103081
PMCID: PMC11144808
PMID: 38795352 [Indexed for MEDLINE]
Conflict of interest statement: Declaration of interests The authors declare no
competing interests.