Rational design of NT-PSMA heterobivalent probes for prostate cancer theranostics
Santo Previti, Sacha Bodin, Emmanuelle Rémond, Delphine Vimont, Elif Hindié, Clément Morgat, Florine Cavelier
RSC Med. Chem.. 2024-01-01; 15(12): 4153-4158
DOI: 10.1039/d4md00491d
Lire sur PubMed
https://www.bordeaux-neurocampus.fr/11696
RSC Med. Chem.. 2024-01-01; 15(12): 4153-4158
DOI: 10.1039/d4md00491d
Lire sur PubMed
https://www.bordeaux-neurocampus.fr/11696
Linker and chelating agents strongly influence the binding affinity of the NTS1-PSMA heterobivalent probe towards NTS1. Comparable affinities between mono- and heterobivalent ligands towards PSMA were observed.