Effects of repeated gravity changes during parabolic flight: Evidence of the need to assist space tourists to outer space
PLoS ONE. 2025-04-23; 20(4): e0320588
DOI: 10.1371/journal.pone.0320588
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In the era of space tourism, walking in the steps of Neil Armstrong has never been more real. Future space tourists will have to face the harshness of the environment, especially the travel, and adapt quickly for their own safety. This issue raises both the question of preparation and the impact of such a journey on novice populations who have not been selected for their physical and cognitive abilities. The objectives of the study are (1) to investigate the impact of space travel on psychophysiological and sensory responses during a parabolic flight experience; (2) to assess recovery from this experience one week later; and (3) to evaluate the relevance of high parasympathetic functioning at baseline as a biomarker of adaptation. Seventeen healthy participants were enrolled in the 79th ESA Parabolic Flight Campaign on board the Airbus A310. Psychological, physiological, and sensory responses were measured at different times from the day before the 3h-flight (baseline) to one week after the flight (recovery). Labels were allocated to two groups according to their parasympathetic functioning at baseline: high parasympathetic (HP) profile and low parasympathetic (LP) profile. At the psychological level, those with an HP profile have a higher coping acceptation and a higher level of interoceptive awareness than the LP profile, except for sleep quality. At the physiological and exteroceptive level, they have a higher heart rate variability, preserved identification of odors and a predisposition to a more adaptive postural response postflight. Nevertheless, postural stability is affected in both profiles, particularly during visual deprivation, while their heart rate variability is increased in both linear and non-linear components. Nevertheless, our results reveal that the recovery constitutes a critical period. Flyers have a decrease of interoceptive awareness and emotions, especially the HP profile. Although the LP profile reported a better subjective sleep quality, both profiles decreased their sleep quality. These results raise the question of the risks that may be induced by space tourism. They highlight two major outcomes: (1) travel of future space tourists does not seem to be at risk as long as the individuals are qualified and fit for the flight and adaptation may be improved by targeting parasympathetic functioning; (2) level of experience has no impact on the psychophysiological and sensory responses. The results highlight the need to monitor the crews over several days and/or to include in the preparation a module allowing them to be prepared for the postflight period and the return to life on Earth. Beyond this, these results contribute to enriching our knowledge of the human challenge of confronting space travel constraints.