Craving changes in first 14 days of addiction treatment: an outcome predictor of 5 years substance use status?

Baillet E(1)(2)(3)(4), Auriacombe M(1)(2), Romao C(1)(2), Garnier H(1)(2), Gauld
C(1)(5)(6), Vacher C(1)(2), Swendsen J(7), Fatseas M(1)(2)(8)(9), Serre
F(10)(11).

Author information:
(1)Univ. Bordeaux, CNRS, SANPSY, UMR 6033, F-33076, Bordeaux, France.
(2)Pôle Interétablissement d’Addictologie, CH Ch. Perrens and CHU de Bordeaux,
F-33076, Bordeaux, France.
(3)Emmanuelle Baillet at time of study was at Univ. Bordeaux, CNRS, SANPSY, UMR
6033, Bordeaux, France.
(4)Department of Psychology, University of California, Berkeley, Berkeley, USA.
(5)Service Psychopathologie du Développement de l’Enfant et de l’Adolescent,
Hospices Civils de Lyon et Université de Lyon 1, Lyon, France.
(6)Institut des Sciences Cognitives Marc Jeannerod, UMR 5229 CNRS, Université
Claude Bernard Lyon 1, Lyon, France.
(7)Univ. Bordeaux, CNRS, INCIA, UMR 5287, Bordeaux, France.
(8)Melina Fatseas at time of study was at Univ. Bordeaux, CNRS, SANPSY, UMR,
6033, Bordeaux, France.
(9)Univ. Bordeaux, CNRS, INCIA, UMR, 5287, Bordeaux, France.
(10)Univ. Bordeaux, CNRS, SANPSY, UMR 6033, F-33076, Bordeaux, France.
.
(11)Pôle Interétablissement d’Addictologie, CH Ch. Perrens and CHU de Bordeaux,
F-33076, Bordeaux, France. .

Addiction is considered a chronic disorder that requires long-term treatment.
Early identification of predictors of outcome may enable better and early
adjustment of treatment. Daily fluctuations of craving have been shown to
predict substance use within hours, making it a major target for treatment. The
objective of this study was to examine whether trajectory and temporal dynamics
of craving, at the initiation of outpatient addiction treatment, were associated
to long-term substance use outcome. An Ecological Momentary Assessment study
collected craving intensity changes and substance use during the first 14-days
of treatment, followed by prospective regular follow-ups for 5 years or more to
assess long-term outcome. Analysis investigated whether individual differences
in craving trajectory (linear trend) and dynamics (inertia, variability and
instability) predicted 5+ years follow-up outcome: substance use (1 day or more
of primary substance use/past 30 days) versus abstinence. Thirty-nine
participants were enrolled in addiction clinic in Bordeaux, France. Results
showed that substance use at 5+ years was significantly associated with slower
decrease of craving intensity (p

Auteurs Bordeaux Neurocampus