Stop and Think about Basal Ganglia Functional Organization: The Pallido-Striatal “Stop” Route
Neuron. 2016-01-01; 89(2): 237-239
DOI: 10.1016/j.neuron.2016.01.003
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Deffains M(1), Iskhakova L(1), Bergman H(2).
Author information:
(1)Department of Medical Neurobiology, Institute of Medical Research
Israel-Canada (IMRIC), The Hebrew University-Hadassah Medical School, Jerusalem,
91120, Israel; The Edmond and Lily Safra Center for Brain Sciences, The Hebrew
University, Jerusalem, 91904, Israel.
(2)Department of Medical Neurobiology, Institute of Medical Research
Israel-Canada (IMRIC), The Hebrew University-Hadassah Medical School, Jerusalem,
91120, Israel; The Edmond and Lily Safra Center for Brain Sciences, The Hebrew
University, Jerusalem, 91904, Israel; Department of Neurosurgery, Hadassah
Medical Center, Jerusalem, 12000, Israel. Electronic address:
.
Comment on
Neuron. 2016 Jan 20;89(2):308-16.
The « arkypallidal » neurons of the globus pallidus (external segment) emit
feedback GABAergic projections to the striatum. In this issue of Neuron, Mallet
et al. (2016) show that « arkypallidal » neurons provide a Stop signal,
suppressing the development of Go-related striatal activity.
Copyright © 2016 Elsevier Inc. All rights reserved.