Huntington’s Disease Human Biology Project Overview
Despite the identification of the gene responsible for Huntington’s disease (HD) over 30 years ago, no treatments yet exist to slow or halt its progression. While animal models have been essential to understanding HD, the most meaningful biological insights—and ultimately, therapeutic breakthroughs—must come from studies in humans. To meet this challenge, the Huntington’s Disease Society of America (HDSA) has adopted a patient-centered research strategy that places human biology at the core of HD research. This initiative supports research that advances our understanding of HD as it occurs in people—through the use of patient samples, clinical data, and collaborations with HD clinics. HDSA encourages researchers to collaborate with one of its Centers of Excellence, but applicants may work with any HD clinic or research site worldwide.