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La lettre / Vendredi 28 août 2026

ACTUS / NEWS

Highlight

Des variants rares du gène PLCG2 qui multiplient le risque de développer la maladie d’Alzheimer

On the agenda

BrainStress: 14-16 October 2026
BrainStress: 14-16 October 2026
Registrations are still open for our international conference! Deadline: October 1st

More information [EN]

Côté UB

COMP 2026-2030 : un cap commun pour toute l'université
COMP 2026-2030 : un cap commun pour toute l'université
Cette feuille de route qui guidera l'établissement jusqu'en 2030.

En savoir plus [FR]
L’université de Bordeaux se dote d’une Commission éthique et déontologie
L’université de Bordeaux se dote d’une Commission éthique et déontologie
Une nouvelle instance pour renforcer notre intégrité collective

En savoir plus [FR]

Offre d'emploi / Job offer

Assistant(e) Ingénieur(e) en biologie et immunohistochimie
Contact : Muriel Koehl (Neurocentre Magendie)

AGENDA


Seminar – Kyriaki Sidiropoulou (Univ. of Crete, Greece)
Wednesday 2 September / 11:00 // Venue: BBS
The role of prefrontal cortex development in the emergence of cognitive symptoms in schizophrenia: Insights from the MAM mouse model
> Invited by Mathieu Wolff (INCIA)

SPARK seminar – Trends and Growth Opportunities Reshaping the Future of the Biopharma Industry: 2026-2040
Wednesday 2 September / 16:00 - 17:30 // Online via Zoom
Speaker: Anantharaman K V

Soutenance de thèse – Christophe Gauld (Sanpsy)
Vendredi 11 septembre / 09:00 // Lieu : Module 1.2
Applications cliniques et neuroscientifiques des réseaux de symptômes : sémiologie, dynamique, intervention et explication

Friday seminar – Camille Lassalle (Barcelona Institute for Global Health, Spain)
Friday 11 September
/ 11:30 // Venue: Centre Broca
From epidemiology to precision nutritional psychiatry: Diet, circadian health, and mental disorders
> Invited by Jean-Christophe Delpech (NutriNeuro)

Seminar – Ulli Bayer (Univ. of Colorado, USA)
Monday 14 September / 11:30 // Venue: Centre Broca
CaMKII in LTP, Alzheimer's disease, and beyond
> Invited by Daniel Choquet (IINS)

Workshops and symposia on registration

Venue: Centre Broca

European Forum for Electroconvulsive Therapy (EFFECT)
18-19 September

Searching for Principles in Motor Control
22-23 September

France Volume-EM first event
28-29 September

Synapse and Network day
Friday 2 October
Registrations will open next week

BrainStress
14-16 October 2026

Sino-French BioImaging Symposium
19-
21 October


NEW PUBLICATIONS


Standardized evaluation of automatic methods for perivascular spaces segmentation in MRI – MICCAI 2024 challenge results
Yilei Wu, Yichi Zhang, Zijian Dong, Fang Ji, An Sen Tan, Gifford Tan, Sizhao Tang, Huijuan Chen, Zijiao Chen, Eric Kwun Kei Ng, Jose Bernal, Hang Min, Ying Xia, Ines Vati, Liz Cooper, Xiaoyu Hu, Yuchen Pei, Yutao Ma, Victor Nozais, Ami Tsuchida, Pierre-Yves Hervé, Philippe Boutinaud, Marc Joliot, Junghwa Kang, Wooseung Kim, Dayeon Bak, Rachika E. Hamadache, Valeriia Abramova, Xavier Lladó, Yuntao Zhu, Zhenyu Gong, Xin Chen, John McFadden, Pek Lan Khong, Roberto Duarte Coello, Hongwei Bran Li, Woon Puay Koh, Christopher Chen, Joanna M. Wardlaw, Maria del C. Valdés Hernández, Juan Helen Zhou.
Medical Image Analysis. 2026-11-01
10.1016/j.media.2026.104227

Divergent tau pathology profiles induced by distinct alpha-synuclein aggregates in non-human primates
Morgane Darricau, Camille Neu-Faber, Mathieu Bourdenx, Sandra Dovero, Gregory Porras, Marie-Laure Thiolat, Ines Trigo-Damas, Nuria Garcia-Carrillo, Maria Trinidad Herrero, Miquel Vila, Jose A Obeso, Vincent Planche, Erwan Bezard, Benjamin Dehay.
Brain. 2026-08-22
10.1093/brain/awag284

Visual Pathways Involvement in Friedreich’s Ataxia Patients Without Macular Impairment
Vincenzo Parisi, Lucilla Barbano, Antonio Di Renzo, Carmen Dell’Aquila, Mattia D’Andrea, Angela Maria Castelluzzo, Gaspare Colacino, Valeria Gioiosa, Gianluca Coppola, Carlo Casali, Lucia Ziccardi.
Journal of Clinical Medicine. 2026-08-05
10.3390/jcm15156097

Le diagnostic sanguin de la maladie d’Alzheimer : utopie ou dystopie ?
Vincent Planche.
Bulletin de l'Académie Nationale de Médecine. 2026-08-01
10.1016/j.banm.2026.05.033

Age-dependent reorganization of behavioral and striatal function in Cntnap2 knockout mice
Mathieu Thabault, Cloé Fernandes-Gomes, Cloé Alcaraz, Anaïs Balbous, Pierre-Olivier Fernagut, Laurie Galvan.
Neurobiology of Disease. 2026-10-01
10.1016/j.nbd.2026.107558

Individual differences in brain cocaine pharmacokinetics predict cocaine intake patterns in rats
Dana Conlisk, Gabriela Goncalves Valente, Jean-François Wiart, Hélène Doat, Florian Hakim, Linda Boone, Mélodie Phanithavong, Camille Richeval, Giulia De Maio, Jean-François Fiancette, Jessica Tostain, Andrea Sepe, Bruno Megarbane, Jean-Michel Gaulier, Véronique Deroche-Gamonet.
Biomedicine & Pharmacotherapy. 2026-09-01
10.1016/j.biopha.2026.119801

GloBIAS survey results – An insight into the global bioimage analysis community
Laura R. de la Ballina, Christa G. Walther, Nicholas D. Condon, Alessandro A. Felder, Martin Schätz, Bettina Schmerl, Ko Sugawara, Clara Prats, Anna Klemm, Kota Miura, Paula Sampaio, Christian Tischer, Shuichi Onami, Rocco D'Antuono, Beth A Cimini, Robert Haase, Agustin A. Corbat, Florian Levet.
Journal of Microscopy. 2026-07-27
10.1111/jmi.70153

A deep learning model for speech-based prediction of clinical scores in people with Huntington’s disease: a longitudinal study with cross-sectional replication
Clément Le Moine Veillon, Sonia Fraisse, Marine Lunven, Audrey Fabre, Katia Youssov, Graça Morgado, Hadrien Titeux, Tiphaine Le Ludec, Cyril Goizet, Cécile Fougeron, Renaud Massart, Anne-Catherine Bachoud-Lévi.
The Lancet Digital Health. 2026-08-01
10.1016/j.landig.2026.101025

Mean-field analysis of a neural network with stochastic spike-timing-dependent plasticity
Pascal Helson, Etienne Tanré, Romain Veltz.
Physical Review E. 2026-08-19
10.1103/fh5w-3zx4

Cannabinoid tolerance relies on CB1 receptor ubiquitination by NEDD4L
Alicia Álvaro-Blázquez, Rui S. Rodrigues, Carlos Montero-Fernández, Marta Isasa, Astrid Cannich, Doriane Gisquet, Ignacio Rodríguez-Crespo, Luigi Bellocchio, Giovanni Marsicano, Carlos Costas-Insua, Manuel Guzmán.
Proceedings of the National Academy of Sciences. 2026-08-25
10.1073/pnas.2606671123

Episodic memory deficits are associated with social cognitive impairments in multiple sclerosis
Bruno Brochet, Thibault Moreau, Aurore Saubusse, Julie Charré-Morin, Delphine Lamargue, Mathilde Deloire, Aurélie Ruet.
Journal of Neurology. 2026-08-20
10.1007/s00415-026-14067-7

Phase separation and protein aggregation in neurodegenerative diseases
Hortense de La Seiglière, Ænora Letourneur, François Ichas, Francesca De Giorgi.
Biophysical Chemistry. 2026-11-01
10.1016/j.bpc.2026.107678

Oxygen-dependent osteocyte transcriptomic adaptations occur without modulation of endothelial gene expression via osteocyte paracrine signaling
Léa Gellée, Frédéric Martins, Alexandre Brochard, Katharina Jähn-Rickert, Delphine B Maurel.
JBMR Plus. 2026-08-19
10.1093/jbmrpl/ziag136

Functional Homology of WIPI4 and Atg18 Enables WDR45 Variant Interpretation for BPAN Diagnosis
Vincent Morin, Christelle M. Durand, Chloé Angelini, Giovanni Stevanin, Patricia Fergelot, Cyril Goizet, Isabelle Coupry, Jean-Paul Lasserre.
International Journal of Molecular Sciences. 2026-08-06
10.3390/ijms27157054

Deep learning reveals a neurocomputational mechanism predicting depression risk in adolescents
Han Lu, Xiaoqian Yan, Benjamin Becker, Andreas Heinz, Barbara J. Sahakian, Christelle Langley, Zhaoyu Zuo, Luolong Cao, Zuo Zhang, Lauren Robinson, Nilakshi Vaidya, Jeanne Winterer, Sinead King, Charlotte Walton, Tobias Banaschewski, Gareth J. Barker, Arun L.W. Bokde, Rüdiger Brühl, Herta Flor, Hugh Garavan, Penny Gowland, Antoine Grigis, Herve Lemaitre, Jean-Luc Martinot, Marie-Laure Paillère Martinot, Eric Artiges, Frauke Nees, Dimitri Papadopoulos Orfanos, Luise Poustka, Hedi Kebir, Ulrike Schmidt, Julia Sinclair, Michael N. Smolka, Sarah Hohmann, Nathalie Holz, Henrik Walter, Robert Whelan, Sylvane Desrivières, Gunter Schumann, Qiang Luo, ,.
Science Advances. 2026-08-07
10.1126/sciadv.aed0772

The multifaceted expression of the gastrin releasing peptide receptor in prostate cancer
Clément Morgat, Mégane Le Quang, Tyrillshall S. T. Damiana, Wytske M. van Weerden, Gaëtan Macgrogan, Valérie Vélasco, Mokrane Yacoub, Marine Gross-Goupil, Elif Hindié, Simone U. Dalm.
Scientific Reports. 2026-08-12
10.1038/s41598-026-64701-7

Prescription Trends for Bipolar Disorder With and Without Comorbid Substance Use and Anxiety Disorders: A Global Bipolar Cohort Collaborative Study
Anastasia K. Yocum, Martin Alda, Bruno Aouizerate, Valerie Aubin, Frank Bellivier, Raoul Belzeaux, Michael Berk, Joanna M. Biernacka, Monika Budde, Katherine E. Burdick, Yun‐Hsuan Chang, Brandon J. Coombes, Philippe Courtet, Nina Dalkner, Claudia Diaz‐Byrd, Caroline Dubertret, Bruno Etain, Giovanna Fico, Janice M. Fullerton, Ophelia Godin, Katherine Gordon‐Smith, Emmanuel Haffen, Dominique Januel, Kamyar Keramatian, Marion Leboyer, Antoine Lefrere, Pierre‐Michel Llorca, Marzieh Majd, Philip B. Mitchell, Benson Mwangi, Emilie Olie, Bronwyn J. Overs, Joanne Petite, Mircea Polosan, Romain Rey, Gloria Roberts, Paul Roux, Ludovic Samalin, Raymund Schwan, Alessandro Serretti, Jair C. Soares, Sarah H. Sperry, Rebecca Strawbridge, Tatjana Stross, Eduard Vieta, Michel Walter, Lana J. Williams, Mon‐Ju Wu, Lakshmi N. Yatham, Allan H. Young, Antoine Yrondi, Giovana B. Zunta‐Soares, Mark A. Frye, Melvin G. McInnis, Balwinder Singh.
Bipolar Disorders. 2026-08-11
10.1111/bdi.70167

Sleep’s influence on susceptibility to motion sickness in parabolic flights and virtual reality: An exploratory study
Tess Bonnard, Līva Araka, Alicia Smith Reina, Jet van Berkel, Carole Morvan, Clément Morgat, Dominique Guehl, Etienne Guillaud, Ellemarije Altena.
Journal of Vestibular Research. 2026-08-10
10.1177/09574271261474571

Academic training selectively shapes the neural pathways mediating sex/gender differences in cognition
Sandrine Cremona, Laure Zago, Christophe Tzourio, Marc Joliot.
Biology of Sex Differences. 2026-08-06
10.1186/s13293-026-00963-0

Association between kynurenine pathway metabolites and psychotropic medications in bipolar disorder: An exploratory study in the FACE-BD cohort
Bruno Etain, Vincent Hennion, Valérie Autier, Sophie Raynal, Ophélia Godin, Bruno Aouizerate, Raoul Belzeaux, Philippe Courtet, Caroline Dubertret, Antoine Lefrere, Emilie Olié, Mircea Polosan, Paul Roux, Raymund Schwan, Ludovic Samalin, Marion Leboyer, Cynthia Marie-Claire, Sophie Gil.
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 2026-08-01
10.1016/j.pnpbp.2026.111891

Connectivity patterns predictive of cognition, but not affect, reflect a segregated intrinsic network architecture
Achille Gillig, Gaël Jobard, Sandrine Cremona, Marc Joliot.
Network Neuroscience. 2026-07-30
10.1162/netn.a.600

Presynaptic actin nanostructures: A reproducibility case study
Rensu P. Theart, Florian Levet, Paul Hernández‐Herrera, Christophe Leterrier, Laura R. de la Ballina.
Journal of Microscopy. 2026-07-24
10.1111/jmi.70138

Estimating the prevalence of amyloid positivity among older adults without dementia in the general population
Lisa Le Scouarnec, Vincent Bouteloup, Timothy Daly, Vincent Planche, Geneviève Chêne, Carole Dufouil for the MEMENTO Study Group.
npj Dementia. 2026-07-21
10.1038/s44400-026-00128-1

P2X4 receptor limits adverse cardiac remodeling following ischemia–reperfusion through regulation of autophagy in cardiac fibroblasts
Ana Valeria Vinhais da Silva, Juliette Strella, Simon Chesseron, Arthur Aupart, Audrey Heraud-Meley, Elodie Miquelestorena-Standley, Marc Ohresser, Ludovica Congiu, Eric Boué-Grabot, Thierry Bourguignon, Sébastien Roger, Stephanie Chadet, Fabrice Ivanes.
Cell Communication and Signaling. 2026-07-10
10.1186/s12964-026-03050-4

Role of hippocampal dentate granule cells in memory: neuronal birth timing matters
Nicolas Blin, Djoher Nora Abrous.
Molecular Psychiatry. 2026-07-21
10.1038/s41380-026-03745-7

Maternal dietary n-3 PUFA deficiency leads to sex-specific alterations in placental and cerebral fatty acid profiles and in oxylipin profiles in the developing mouse brain
Flore Marchaland, Maud Martinat, Mathieu Di Miceli, Stéphane Grégoire, Moïra Rossitto, Lydie Morel, Agnès Aubert, Alexandra Séré, Jean-Christophe Delpech, Corinne Joffre, Niyazi Acar, Richard P. Bazinet, Sophie Layé.
Biochimie. 2026-07-01
10.1016/j.biochi.2026.07.010

What the “FakeMed”? Or “fake medicines” according to a collective of French doctors. Corrected and republished article
Fabrice Berna, Jean-Arthur Micoulaud-Franchi, François Paille, Julien Nizard, Laurence Verneuil.
Douleurs : Évaluation - Diagnostic - Traitement. 2026-07-01
10.1016/j.douler.2026.06.001

Tourette syndrome: brain neurophysiology, circuit dysfunction, and neuromodulation across invasive and noninvasive approaches
Yulia Worbe, Edouard Courtin.
Current Opinion in Neurology. 2026-06-05
10.1097/wco.0000000000001500

Natural history and 12-month progression of multiple system atrophy in a Chinese cohort
Tao Feng, Han Wang, Jian Wang, Beisha Tang, Chun-feng Liu, Haibo Chen, Wei Mao, Qian Zhou, Olivier Rascol, Wassilios G. Meissner, Aroussi Bidani, Andreas Rieckmann, Daniel Oudin Åström, Piu Chan, Huifang Shang, Liying Cui.
BMC Neurology. 2026-06-12
10.1186/s12883-026-05037-7

Reference-point dependent reinforcement learning in humans and rats
Lachlan A. Ferguson, Magdalena Soukupova, Sébastien Bouret, Stefano Palminteri, Shauna L. Parkes.
Nature Communications. 2026-05-28
10.1038/s41467-026-73623-x

Inflammatory and immune profiling in children and adolescents with attention-deficit/hyperactivity disorder (ADHD): a matched case–control study with longitudinal on/off psychostimulant assessment (ANIME)
Erica Fongaro, Quentin Leyrolle, Charlotte Madore, Sylvain Lehmann, Marie-Christine Picot, Sophie Laye, Diane Purper-Ouakil.
BMC Psychiatry. 2026-03-27
10.1186/s12888-026-08012-1

Un chercheur inspiré et vagabond : Charles-Édouard Brown-Séquard (1817–1894)
André Calas.
Biologie Aujourd’hui. 2026-01-01
10.1051/jbio/2026004

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