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	<title>Pathologic brain – Pathophysiology and translational research &#8211; Bordeaux Neurocampus</title>
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	<link>https://www.bordeaux-neurocampus.fr</link>
	<description>Département de neurosciences de l’université de Bordeaux.</description>
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	<title>Pathologic brain – Pathophysiology and translational research &#8211; Bordeaux Neurocampus</title>
	<link>https://www.bordeaux-neurocampus.fr</link>
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		<title>Endocannabinoids and neuroadaptation</title>
		<link>https://www.bordeaux-neurocampus.fr/team/endocannabinoids-and-neuroadaptation/</link>
		
		<dc:creator><![CDATA[Giovanni Marsicano]]></dc:creator>
		<pubDate>Thu, 07 Jun 2018 16:10:38 +0000</pubDate>
				<category><![CDATA[Apprentissage]]></category>
		<category><![CDATA[Bioénergétique du cerveau et physiologie]]></category>
		<category><![CDATA[cannabinoïdes]]></category>
		<category><![CDATA[cannabis]]></category>
		<category><![CDATA[Cognition]]></category>
		<category><![CDATA[Emotion]]></category>
		<category><![CDATA[endocannabinoïdes]]></category>
		<category><![CDATA[Energétique et Mitochondrie]]></category>
		<category><![CDATA[Excitabilité neuronale]]></category>
		<category><![CDATA[Formation et fonctionnement des circuits neuronaux]]></category>
		<category><![CDATA[Interactions neurones-glie]]></category>
		<category><![CDATA[Mémoire]]></category>
		<category><![CDATA[Métabolisme]]></category>
		<category><![CDATA[Neurophysiologie]]></category>
		<category><![CDATA[Plasticité des réseaux]]></category>
		<category><![CDATA[Plasticité synaptique]]></category>
		<category><![CDATA[récepteurs CB1]]></category>
		<category><![CDATA[Schizophrénie]]></category>
		<category><![CDATA[Stress]]></category>
		<category><![CDATA[Système olfactif]]></category>
		<category><![CDATA[Troubles addictifs]]></category>
		<category><![CDATA[Troubles anxieux]]></category>
		<category><![CDATA[Troubles des comportements alimentaires]]></category>
		<category><![CDATA[Troubles du comportement]]></category>
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					<description><![CDATA[Our team aims at uncovering the functions of the endocannabinoid system in the brain as well as the cannabinoids regulation of behavior and psychotic disorders. By using conditional mutagenesis, we are currently dissecting the roles of cannabinoid receptors type-1 (CB1) in different cellular and subcellular localizations towards a better understanding of the general rules governing behavior such as memory, locomotor activity and olfaction. Innovative techniques : mitochondrial dynamic and function assessment, voltage-sensitive dye imaging (VSDI), in vivo &#038; ex vivo electrophysiology, transgenic mice, in situ hybridization.]]></description>
		
		
		
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		<title>Energy balance and obesity</title>
		<link>https://www.bordeaux-neurocampus.fr/team/energy-balance-and-obesity/</link>
		
		<dc:creator><![CDATA[Cota Daniela]]></dc:creator>
		<pubDate>Thu, 07 Jun 2018 16:10:22 +0000</pubDate>
				<category><![CDATA[Bioénergétique du cerveau et physiologie]]></category>
		<category><![CDATA[Comportement alimentaire]]></category>
		<category><![CDATA[Métabolisme]]></category>
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					<description><![CDATA[The main focus of our research is the understanding of the regulation of food intake and body weight. Our work is focused on the role of the mammalian target of rapamycin (mTOR), a cellular fuel sensor, and the endocannabinoid system (ECS) in controlling food intake and energy expenditure. We are identifying neuronal substrates and cellular mechanisms underlying the action of the mTOR pathway within the hypothalamus. We currently aim at understanding the relationship between cannabinoids type1 receptor (a molecular actor of the ECS) and mTORC1-dependent signaling in the control of neuronal circuits regulating food intake and body weight. Our work&#8230;]]></description>
		
		
		
			</item>
		<item>
		<title>Neuroimmunology of metabolic health and disease (NOMAD)</title>
		<link>https://www.bordeaux-neurocampus.fr/team/neuroimmunology-lab/</link>
		
		<dc:creator><![CDATA[claireDLTTR]]></dc:creator>
		<pubDate>Thu, 04 Sep 2025 09:18:52 +0000</pubDate>
				<category><![CDATA[cellules immunitaires]]></category>
		<category><![CDATA[maladies neurodégénératives]]></category>
		<category><![CDATA[métabolisme énergique]]></category>
		<category><![CDATA[Microglie]]></category>
		<category><![CDATA[neuroimmunologie]]></category>
		<guid isPermaLink="false">https://www.bordeaux-neurocampus.fr/?post_type=team&#038;p=187497</guid>

					<description><![CDATA[Our team studies how the immune system and the central nervous system communicate, both under healthy conditions and during disease. We are particularly interested in how this two-way “neuroimmune” dialogue shapes whole-body metabolism, in both males and females. A major focus of our research is the interaction between microglia—the brain’s resident immune cells—and neurons. We explore how these interactions are influenced by diet, with a special emphasis on the role of lipids in regulating microglial physiology. Beyond microglia, we also investigate how other types of immune cells contribute to systemic metabolic regulation. To address these questions, we combine a broad range&#8230;]]></description>
		
		
		
			</item>
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		<title>Pathophysiology of proteinopathies</title>
		<link>https://www.bordeaux-neurocampus.fr/team/pathophysiology-of-proteinopathies/</link>
		
		<dc:creator><![CDATA[Bezard Erwan]]></dc:creator>
		<pubDate>Thu, 07 Jun 2018 16:10:22 +0000</pubDate>
				<category><![CDATA[alpha-synucléine]]></category>
		<category><![CDATA[Alzheimer]]></category>
		<category><![CDATA[Atrophie multi-systématisée]]></category>
		<category><![CDATA[Démences]]></category>
		<category><![CDATA[Motricité]]></category>
		<category><![CDATA[Mouvement]]></category>
		<category><![CDATA[Parkinson]]></category>
		<category><![CDATA[Tau]]></category>
		<guid isPermaLink="false">https://neurodev-ng.u-bordeaux.fr/team/pathophysiology-of-parkinsonian-syndrome/</guid>

					<description><![CDATA[Our translational research is dedicated to uncovering the pathophysiology of Parkinsons disease and works towards development of therapeutic solutions. Our team is best known for its work on L-DOPA-induced dyskinesia (LID), serious motor complications associated to the chronic dopamine replacement therapy. Recently, we work on a collaborative project using innovative nanotechnology as a new means of imaging living systems and of delivering therapy. Innovative techniques: Optical nanoprobes, lysososomal targeted nanoparticles, kinematics, gene transfer, preclinical studies]]></description>
		
		
		
			</item>
		<item>
		<title>Psychobiology of vulnerability to drug addiction</title>
		<link>https://www.bordeaux-neurocampus.fr/team/psychobiology-of-drug-addiction/</link>
		
		<dc:creator><![CDATA[Véronique Deroche-Gamonet]]></dc:creator>
		<pubDate>Thu, 07 Jun 2018 16:10:38 +0000</pubDate>
				<category><![CDATA[Comportement]]></category>
		<category><![CDATA[Neuroadaptations]]></category>
		<category><![CDATA[Toxicomanie]]></category>
		<category><![CDATA[Troubles addictifs]]></category>
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					<description><![CDATA[Our team works at the understanding of the psychobiological mechanisms of addiction, notably to cocaine and tobacco. Drug use can lead to behavioral disorders of which an extreme version is addiction. This psychopathology is not a mere excessive drug use, but is defined as a loss of control over use, which is particularly reflected in the maintenance of use despite its adverse effects. Critically, all users are not equally at risk for addiction, however. Our experimental strategy consists in integrating these characteristics of the pathology, i.e. loss of control over drug use and individual vulnerability, for an increased face and&#8230;]]></description>
		
		
		
			</item>
		<item>
		<title>Sleep, addiction and neuropsychiatry</title>
		<link>https://www.bordeaux-neurocampus.fr/team/team-sanpsy/</link>
		
		<dc:creator><![CDATA[Jean-Marc Alexandre]]></dc:creator>
		<pubDate>Thu, 07 Jun 2018 16:10:22 +0000</pubDate>
				<category><![CDATA[addiction]]></category>
		<category><![CDATA[Cognition]]></category>
		<category><![CDATA[Cohorte de patients]]></category>
		<category><![CDATA[Comportement]]></category>
		<category><![CDATA[Craving]]></category>
		<category><![CDATA[Emotion]]></category>
		<category><![CDATA[Fonctions exécutives]]></category>
		<category><![CDATA[Intelligence artificielle et réalité virtuelle]]></category>
		<category><![CDATA[Interfaces humain-machine et Santé connectée]]></category>
		<category><![CDATA[Motivation]]></category>
		<category><![CDATA[Prise de décision]]></category>
		<category><![CDATA[Psychiatrie]]></category>
		<category><![CDATA[Rechute]]></category>
		<category><![CDATA[Troubles addictifs]]></category>
		<category><![CDATA[Troubles du comportement]]></category>
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					<description><![CDATA[We study substance and non-substance addiction and have developed a human model of addiction. Our studies tend to better characterize the common phenomenology accross addictions and its determinants, using a multidisciplinary approach (clinical neurobiology, epidemiology, psychology and sociology), with a special interest on craving and its behavioral correlates. The main research tool is an open prospective cohort (ADDICTAQUI) started in 1994, of over 3500 patients requesting treatment for addiction. Innovative techniques: Patient prospective cohort, Addiction Severity Index, Ecological Momentary Assesment]]></description>
		
		
		
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