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	<title>Formation et fonctionnement des circuits neuronaux &#8211; Bordeaux Neurocampus</title>
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	<link>https://www.bordeaux-neurocampus.fr</link>
	<description>Département de neurosciences de l’université de Bordeaux.</description>
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	<title>Formation et fonctionnement des circuits neuronaux &#8211; Bordeaux Neurocampus</title>
	<link>https://www.bordeaux-neurocampus.fr</link>
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		<title>Cortical plasticity</title>
		<link>https://www.bordeaux-neurocampus.fr/team/cortical-plasticity/</link>
		
		<dc:creator><![CDATA[Frick Andreas]]></dc:creator>
		<pubDate>Thu, 07 Jun 2018 16:10:38 +0000</pubDate>
				<category><![CDATA[Apprentissage]]></category>
		<category><![CDATA[ASDs (Autism Spectrum Disorders)]]></category>
		<category><![CDATA[Assemblées neuronales]]></category>
		<category><![CDATA[Attention]]></category>
		<category><![CDATA[Bio-informatique et analyse des données]]></category>
		<category><![CDATA[Codage et intégration du signal]]></category>
		<category><![CDATA[Connectivité]]></category>
		<category><![CDATA[Excitabilité neuronale]]></category>
		<category><![CDATA[Formation et fonctionnement des circuits neuronaux]]></category>
		<category><![CDATA[Fragile X]]></category>
		<category><![CDATA[Imagerie cellulaire in vitro ou in vivo]]></category>
		<category><![CDATA[Maladies Neuro-développementales]]></category>
		<category><![CDATA[Maladies rares]]></category>
		<category><![CDATA[Mémoire]]></category>
		<category><![CDATA[Mémorisation des perceptions sensorielles]]></category>
		<category><![CDATA[Neurophysiologie]]></category>
		<category><![CDATA[Physiologie synaptique]]></category>
		<category><![CDATA[Plasticité des réseaux]]></category>
		<category><![CDATA[Plasticité synaptique]]></category>
		<category><![CDATA[Processus de l'information sensorielle]]></category>
		<category><![CDATA[Retard mental]]></category>
		<category><![CDATA[traçage viral]]></category>
		<guid isPermaLink="false">https://neurodev-ng.u-bordeaux.fr/team/cortical-plasticity/</guid>

					<description><![CDATA[Our research topic is focused on the structure, function and dynamic regulation of cortical circuits in various conditions such as learning, development and disease. We investigate ion channel function in the different neuronal compartment to predict/analyse the coding properties of cortical neurons alone or in cell assembly. Using genetic models, we revealed the implication of ion channel dysfunctions in the hypersensitivity in response to sensory stimuli associated to neocortical hyperexcitability, features of fragile X syndrome and autism. We also study the anatomical connectivity of neocortical circuits and showed that its alterations named as a "connectopathy," cause functional defects that may&#8230;]]></description>
		
		
		
			</item>
		<item>
		<title>Decision and adaptation (DECAD)</title>
		<link>https://www.bordeaux-neurocampus.fr/team/decision-and-adaptation/</link>
		
		<dc:creator><![CDATA[Mathieu Wolff]]></dc:creator>
		<pubDate>Thu, 07 Jun 2018 16:10:38 +0000</pubDate>
				<category><![CDATA[Analyses des données]]></category>
		<category><![CDATA[Apprentissage]]></category>
		<category><![CDATA[Assemblées neuronales]]></category>
		<category><![CDATA[Attention]]></category>
		<category><![CDATA[Codage et intégration du signal]]></category>
		<category><![CDATA[Cognition]]></category>
		<category><![CDATA[Comportement]]></category>
		<category><![CDATA[Comportement alimentaire]]></category>
		<category><![CDATA[Connectivité]]></category>
		<category><![CDATA[Dépression]]></category>
		<category><![CDATA[Déséquilibre alimentaire et vulnérabilité psychiatrique]]></category>
		<category><![CDATA[Emotion]]></category>
		<category><![CDATA[Fonctions exécutives]]></category>
		<category><![CDATA[Formation et fonctionnement des circuits neuronaux]]></category>
		<category><![CDATA[Mémoire]]></category>
		<category><![CDATA[Motivation]]></category>
		<category><![CDATA[Optogénétique]]></category>
		<category><![CDATA[Optogénétique et chemogénétique]]></category>
		<category><![CDATA[Prise de décision]]></category>
		<category><![CDATA[Schizophrénie]]></category>
		<category><![CDATA[Troubles anxieux]]></category>
		<category><![CDATA[Troubles des comportements alimentaires]]></category>
		<category><![CDATA[Troubles du comportement]]></category>
		<guid isPermaLink="false">https://neurodev-ng.u-bordeaux.fr/team/decision-and-adaptation/</guid>

					<description><![CDATA[The scope of our team is to understand the neurobehavioral mechanisms involved in decision-making. This work relies on sophisticated behavioural paradigms understanding the action-outcome relationships in goal-directed responses. The originality of our research is to integrate cognitive neuroscience and behavioural psychology in rodent trained in complex operant tasks. The use of pharmacological and genetic tools implemented by meta-analyses allows us to reveal the neural circuits underlying behavioural flexibility and adapted behaviour. We characterised functional thalamic nuclei and identified a maturation period of the dopamine meso-prefrontal system during adolescence that may explain some form of impulsive behaviour observed during this period.&#8230;]]></description>
		
		
		
			</item>
		<item>
		<title>Development and Neurobiology of Neural Networks (DN3)</title>
		<link>https://www.bordeaux-neurocampus.fr/team/development-and-neurobiology-of-neural-networks/</link>
		
		<dc:creator><![CDATA[&#102;&#114;ancoi&#115;.&#108;&#97;mb&#101;rt&#64;&#117;-b&#111;&#114;d&#101;&#97;&#117;x&#46;&#102;&#114;]]></dc:creator>
		<pubDate>Thu, 07 Jun 2018 16:10:50 +0000</pubDate>
				<category><![CDATA[Assemblées neuronales]]></category>
		<category><![CDATA[Codage et intégration du signal]]></category>
		<category><![CDATA[Connectivité]]></category>
		<category><![CDATA[Développement du système nerveux]]></category>
		<category><![CDATA[Excitabilité neuronale]]></category>
		<category><![CDATA[Formation et fonctionnement des circuits neuronaux]]></category>
		<category><![CDATA[Motricité]]></category>
		<category><![CDATA[Mouvement]]></category>
		<category><![CDATA[Neurophysiologie]]></category>
		<category><![CDATA[Optogénétique]]></category>
		<category><![CDATA[Physiologie synaptique]]></category>
		<category><![CDATA[Plasticité des réseaux]]></category>
		<category><![CDATA[Plasticité synaptique]]></category>
		<category><![CDATA[Système auditif et d’équilibration]]></category>
		<guid isPermaLink="false">https://neurodev-ng.u-bordeaux.fr/team/organization-and-adaptability-of-motor-systems/</guid>

					<description><![CDATA[Our overall research objective is to decipher the neuronal basis of the short- and long-term functional plasticity of motor systems. In particular, we are characterising during embryonic development the synaptic and neuromodulatory properties of the preBötzinger complex neurons that drives respiratory oscillations. We also study the neuronal flexibility of respiration and locomotion oscillatory systems that function separately or spontaneously coordinate their action in given conditions (i.e. physical activity). The principal experimental goal of our work is to causally link cellular, synaptic and neural network physiology to particular aspects of adaptive behaviour. Innovative techniques: Electrophysiology, electrochemistry, dynamic clamp, calcium imaging, neuropharmacology,&#8230;]]></description>
		
		
		
			</item>
		<item>
		<title>Endocannabinoids and neuroadaptation</title>
		<link>https://www.bordeaux-neurocampus.fr/team/endocannabinoids-and-neuroadaptation/</link>
		
		<dc:creator><![CDATA[Giovanni Marsicano]]></dc:creator>
		<pubDate>Thu, 07 Jun 2018 16:10:38 +0000</pubDate>
				<category><![CDATA[Apprentissage]]></category>
		<category><![CDATA[Bioénergétique du cerveau et physiologie]]></category>
		<category><![CDATA[cannabinoïdes]]></category>
		<category><![CDATA[cannabis]]></category>
		<category><![CDATA[Cognition]]></category>
		<category><![CDATA[Emotion]]></category>
		<category><![CDATA[endocannabinoïdes]]></category>
		<category><![CDATA[Energétique et Mitochondrie]]></category>
		<category><![CDATA[Excitabilité neuronale]]></category>
		<category><![CDATA[Formation et fonctionnement des circuits neuronaux]]></category>
		<category><![CDATA[Interactions neurones-glie]]></category>
		<category><![CDATA[Mémoire]]></category>
		<category><![CDATA[Métabolisme]]></category>
		<category><![CDATA[Neurophysiologie]]></category>
		<category><![CDATA[Plasticité des réseaux]]></category>
		<category><![CDATA[Plasticité synaptique]]></category>
		<category><![CDATA[récepteurs CB1]]></category>
		<category><![CDATA[Schizophrénie]]></category>
		<category><![CDATA[Stress]]></category>
		<category><![CDATA[Système olfactif]]></category>
		<category><![CDATA[Troubles addictifs]]></category>
		<category><![CDATA[Troubles anxieux]]></category>
		<category><![CDATA[Troubles des comportements alimentaires]]></category>
		<category><![CDATA[Troubles du comportement]]></category>
		<guid isPermaLink="false">https://neurodev-ng.u-bordeaux.fr/team/endocannabinoids-and-neuroadaptation/</guid>

					<description><![CDATA[Our team aims at uncovering the functions of the endocannabinoid system in the brain as well as the cannabinoids regulation of behavior and psychotic disorders. By using conditional mutagenesis, we are currently dissecting the roles of cannabinoid receptors type-1 (CB1) in different cellular and subcellular localizations towards a better understanding of the general rules governing behavior such as memory, locomotor activity and olfaction. Innovative techniques : mitochondrial dynamic and function assessment, voltage-sensitive dye imaging (VSDI), in vivo &#038; ex vivo electrophysiology, transgenic mice, in situ hybridization.]]></description>
		
		
		
			</item>
		<item>
		<title>Hybrid sensorimotor control</title>
		<link>https://www.bordeaux-neurocampus.fr/team/hybrid-sensorimotor-performance/</link>
		
		<dc:creator><![CDATA[Rugy Aymar de]]></dc:creator>
		<pubDate>Thu, 07 Jun 2018 16:10:50 +0000</pubDate>
				<category><![CDATA[Apprentissage]]></category>
		<category><![CDATA[Codage et intégration du signal]]></category>
		<category><![CDATA[Comportement]]></category>
		<category><![CDATA[Connectivité]]></category>
		<category><![CDATA[Fonctions exécutives]]></category>
		<category><![CDATA[Formation et fonctionnement des circuits neuronaux]]></category>
		<category><![CDATA[Handicap]]></category>
		<category><![CDATA[Intelligence artificielle et réalité virtuelle]]></category>
		<category><![CDATA[Interfaces humain-machine et Santé connectée]]></category>
		<category><![CDATA[Modélisation des neurones et des réseaux de neurones]]></category>
		<category><![CDATA[Motricité]]></category>
		<category><![CDATA[Mouvement]]></category>
		<guid isPermaLink="false">https://neurodev-ng.u-bordeaux.fr/team/hybrid-sensorimotor-performance/</guid>

					<description><![CDATA[Our team uses hybrid systems, which mix biological control with artificial devices, in order to (i) increase our understanding of sensorimotor control and (ii) exploit this knowledge to restore and optimize movement. Instead of being pre-programmed in the brain, movement coordination largely depends upon multiple feedback loops that operate at different levels of the sensorimotor control system. For instance, muscle mechanics provides an instantaneous functional response to small perturbations, while segmental and transcortical reflexes are able to absorb increasingly larger perturbations by precisely coordinating muscle responses for the complex musculoskeletal design of our limbs. These loops are typically violated in&#8230;]]></description>
		
		
		
			</item>
		<item>
		<title>Mechanisms of Adaptive Processes in brain circuits (MAP)</title>
		<link>https://www.bordeaux-neurocampus.fr/team/mechanisms-of-adaptive-processes-in-brain-circuits/</link>
		
		<dc:creator><![CDATA[Mathieu Letellier]]></dc:creator>
		<pubDate>Tue, 09 Jan 2024 16:37:10 +0000</pubDate>
				<category><![CDATA[Adhésion cellulaire et cytosquelette]]></category>
		<category><![CDATA[ASDs (Autism Spectrum Disorders)]]></category>
		<category><![CDATA[Bio-informatique et analyse des données]]></category>
		<category><![CDATA[Complexes moléculaires de la synapse]]></category>
		<category><![CDATA[Connectivité]]></category>
		<category><![CDATA[Développement du système nerveux]]></category>
		<category><![CDATA[Formation et fonctionnement des circuits neuronaux]]></category>
		<category><![CDATA[Imagerie cellulaire in vitro ou in vivo]]></category>
		<category><![CDATA[Interactions neurones-glie]]></category>
		<category><![CDATA[Maladies Neuro-développementales]]></category>
		<category><![CDATA[Microscopie super-résolutive]]></category>
		<category><![CDATA[Neurophysiologie]]></category>
		<category><![CDATA[Optogénétique]]></category>
		<category><![CDATA[Optogénétique et chemogénétique]]></category>
		<category><![CDATA[Physiologie synaptique]]></category>
		<category><![CDATA[Plasticité synaptique]]></category>
		<category><![CDATA[transcriptomique]]></category>
		<category><![CDATA[Viral tracing]]></category>
		<guid isPermaLink="false">https://www.bordeaux-neurocampus.fr/?post_type=team&#038;p=166552</guid>

					<description><![CDATA[The brain's ability to constantly adapt its organization to ever-changing stimuli is termed "plasticity" and is a prominent feature of learning and memory in adults, as well as the assembly of neuronal circuits during critical developmental periods. Connections that convey relevant information and are the most active become stronger and stabilize, while less active ones weaken and eventually get eliminated, optimizing the storage and processing of information in the brain. Our research aims to examine the molecular and cellular mechanisms underlying these adaptive processes. We employ a multidisciplinary approach, including single-cell manipulation, electrophysiology, optogenetics, single-cell RNA sequencing, and high-resolution imaging,&#8230;]]></description>
		
		
		
			</item>
		<item>
		<title>Monoamines, Parkinson and Pain</title>
		<link>https://www.bordeaux-neurocampus.fr/team/neurochemistry-deep-brain-stimulation-and-parkinsons-disease/</link>
		
		<dc:creator><![CDATA[Benazzouz Abdelhamid]]></dc:creator>
		<pubDate>Thu, 07 Jun 2018 16:10:22 +0000</pubDate>
				<category><![CDATA[Douleur]]></category>
		<category><![CDATA[Formation et fonctionnement des circuits neuronaux]]></category>
		<category><![CDATA[Neurophysiologie]]></category>
		<category><![CDATA[Optogénétique]]></category>
		<category><![CDATA[Parkinson]]></category>
		<guid isPermaLink="false">https://neurodev-ng.u-bordeaux.fr/team/neurochemistry-deep-brain-stimulation-and-parkinsons-disease/</guid>

					<description><![CDATA[Our research project aims to better understand the pathophysiology of Parkinsons disease in order to improve the existing therapeutic approaches and to develop new therapies for the disease. Currently, we especially focus our work on the role of monoaminergic systems (noradrenaline, dopamine, serotonin) in the pathophysiology and therapy of Parkinsons disease. The team is acknowledged for its neurochemical and electrophysiological inputs unraveling the mechanisms of action of the deep brain stimulation of the subthalamic nucleus and L-DOPA medication in animal models of Parkinsons disease. Innovative techniques: multisite intracerebral microdialysis, motor and non-motor behaviors, in vivo electrophysiology.]]></description>
		
		
		
			</item>
		<item>
		<title>Motoneurons and synaptic partners (MotoPSyn)</title>
		<link>https://www.bordeaux-neurocampus.fr/team/motopsyn/</link>
		
		<dc:creator><![CDATA[didierLeRay]]></dc:creator>
		<pubDate>Thu, 07 Jun 2018 16:10:22 +0000</pubDate>
				<category><![CDATA[ASDs (Autism Spectrum Disorders)]]></category>
		<category><![CDATA[Assemblées neuronales]]></category>
		<category><![CDATA[Connectivité]]></category>
		<category><![CDATA[Développement du système nerveux]]></category>
		<category><![CDATA[Formation et fonctionnement des circuits neuronaux]]></category>
		<category><![CDATA[Motricité]]></category>
		<category><![CDATA[Mouvement]]></category>
		<category><![CDATA[Neurophysiologie]]></category>
		<category><![CDATA[Plasticité des réseaux]]></category>
		<category><![CDATA[Plasticité synaptique]]></category>
		<category><![CDATA[Sclérose latérale amyotrophique]]></category>
		<category><![CDATA[Sensory information processing]]></category>
		<category><![CDATA[Troubles des comportements chez l’enfant et l’adolescent]]></category>
		<guid isPermaLink="false">https://neurodev-ng.u-bordeaux.fr/team/development-of-neuronal-networks-in-normal-and-pathological-conditions/</guid>

					<description><![CDATA[The objective of our team is to understand the mechanisms involved in the function of mammal spinal motor networks from its embryonic development to its pathological conditions, such as amyotrophic lateral sclerosis, ALS. In particular, we focus our efforts on: 1) deciphering the role of GABAergic interneuron in the genesis of spontaneous activity at early developmental stages and 2) identifying cellular and molecular mechanisms involved in the early motor deficits observed in spinal motoneurons from ALS mouse models. Innovative techniques &#124; electrophysiology in vitro, ALS mouse models]]></description>
		
		
		
			</item>
		<item>
		<title>Neurophysiology of natural behaviors</title>
		<link>https://www.bordeaux-neurocampus.fr/team/neurophysiology-of-natural-behaviors/</link>
		
		<dc:creator><![CDATA[Lisa Roux]]></dc:creator>
		<pubDate>Tue, 17 Jul 2018 08:41:12 +0000</pubDate>
				<category><![CDATA[Analyses des données]]></category>
		<category><![CDATA[Apprentissage]]></category>
		<category><![CDATA[Assemblées neuronales]]></category>
		<category><![CDATA[Codage et intégration du signal]]></category>
		<category><![CDATA[Comportement]]></category>
		<category><![CDATA[Formation et fonctionnement des circuits neuronaux]]></category>
		<category><![CDATA[Mémoire]]></category>
		<category><![CDATA[Mémorisation des perceptions sensorielles]]></category>
		<category><![CDATA[Neurocomputation]]></category>
		<category><![CDATA[Neurophysiologie]]></category>
		<category><![CDATA[Optogénétique]]></category>
		<category><![CDATA[Optogénétique et chemogénétique]]></category>
		<category><![CDATA[Plasticité des réseaux]]></category>
		<category><![CDATA[Sommeil - Troubles du sommeil]]></category>
		<category><![CDATA[Système olfactif]]></category>
		<guid isPermaLink="false">https://neurodev-ng.u-bordeaux.fr/?post_type=team&#038;p=62033</guid>

					<description><![CDATA[The ability to store and retrieve associations between specific sensory stimuli and behaviorally relevant information is a vital memory function: it allows the organism to adapt its behavior based on prior experience. Olfaction is a central sensory modality in rodents as it supports an array of crucial behaviors such as predator avoidance, feeding, reproduction, maternal behavior and social interactions. Although specific odors can trigger innate responses, most odor stimuli acquire behavioral significance upon learning and experience. The goal of our team is to identify the network mechanisms underlying the formation of olfactory memory traces across distributed brain regions. More generally,&#8230;]]></description>
		
		
		
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