axe HPA Archives - Bordeaux Neurocampus https://www.bordeaux-neurocampus.fr/tag/axe-hpa/ Département de neurosciences de l’université de Bordeaux. Mon, 22 Dec 2025 11:45:42 +0000 fr-FR hourly 1 https://wordpress.org/?v=7.0.4 https://www.bordeaux-neurocampus.fr/wp-content/uploads/2018/03/cropped-favicon-neurocampus-512px-8bits-80x80.png axe HPA Archives - Bordeaux Neurocampus https://www.bordeaux-neurocampus.fr/tag/axe-hpa/ 32 32 Muriel Darnaudéry https://www.bordeaux-neurocampus.fr/staff/muriel-darnaudery/ Sat, 28 Jul 2018 20:54:16 +0000 https://neurodev-ng.u-bordeaux.fr/staff/muriel-darnaudery/ I am working on the hypothesis of the developmental origin of adult health and diseases using an integrative approach. My research is dedicated to the exploration of the role of early-life environment (nutrition, maternal obesity, maternal diabetes, maternal stress) on brain functions and vulnerability to neuropsychiatric diseases (depression, anxiety) in offspring using preclinical models. Our work indicates that adverse early-life events (both during pre- and postnatal periods) increase the allostatic load and program the brain vulnerability to stress later in life. I also explore the causal role of gut-brain dysfunctions (gut microbiota dysbiosis and gut leakiness) in the emergence of…

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