addiction Archives - Bordeaux Neurocampus

Le sucre, aussi addictif qu’une drogue ?

Arnaud Rodriguez — Sun, 15 Jul 2018 07:21:09 +0000

Interview de Serge Ahmed dans le magazine Psychologies.

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Vincent David et al in Journal of Neuroscience

Arnaud Rodriguez — Thu, 23 Jul 2020 17:46:56 +0000

β4-Nicotinic Receptors Are Critically Involved in Reward-Related Behaviors and Self-Regulation of Nicotine Reinforcement.

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Choice, Addiction and Neurodysfunctions (Candy)

Michel Engeln — Thu, 07 Jun 2018 16:10:22 +0000

Our research aims at identifying the psychological and neurobiological determinants of the different stages of addiction, drug choices and preferences in order to develop/improve strategies to prevent relapse. To successfully tackle these goals, we compare drug- versus nondrug-preferring rats to elucidate the psychological and neurobiological substrates underlying the abnormal preference for the drug. Our efforts are also concentrated in investigating the long-term preventive effects of a cue exposure procedure against relapse to reveal the brain regions that play a critical role in interoception, behavioral inhibition and motivation. Innovative techniques: in vivo recording, behavioral procedures for drug choices and preferences

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Emotion, Motivation and Cognition (EMOTIV)

vincentDavid — Thu, 07 Jun 2018 16:10:22 +0000

Our research is interested in the interactions between emotions and cognitive processes in normal conditions and pathological states (short and long-stress, aging, disease, addiction). Our main project aims at characterizing the neuronal substrates underlying the positive and negative emotion-memory interaction in normal young adult mice. We also study how the emotional impact on memory is altered by aging or in pathological states such as in Alzheimers disease, chronic alcohol and diencephalic dementia, to possibly restore the impaired memory functions. Innovative techniques: microdialysis, corticosterone assays, electrophysiology, rodent behavioural paradigms

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Physiopathology and therapeutic approaches of stress-related diseases

Jean-Michel Revest — Thu, 07 Jun 2018 16:10:50 +0000

Our team aims at characterizing the neurobiological basis of addiction and molecular basis of traumatic memories. By applying a translational research, our work is dedicated to offer and develop new treatment for addiction. We successfully revealed neurobiological substrates involved in the transition to cocaine addiction. We recently demonstrated that pregnenolone can protect the brain from cannabis intoxication, that serves as a ground for clinical research. Innovative techniques: neurosteroids biochemistry, In vivo HPLC-microdialysis, model of addiction, rodent behavioral testing.

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Sleep, addiction and neuropsychiatry

Jean-Marc Alexandre — Thu, 07 Jun 2018 16:10:22 +0000

We study substance and non-substance addiction and have developed a human model of addiction. Our studies tend to better characterize the common phenomenology accross addictions and its determinants, using a multidisciplinary approach (clinical neurobiology, epidemiology, psychology and sociology), with a special interest on craving and its behavioral correlates. The main research tool is an open prospective cohort (ADDICTAQUI) started in 1994, of over 3500 patients requesting treatment for addiction. Innovative techniques: Patient prospective cohort, Addiction Severity Index, Ecological Momentary Assesment

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