Neuronal Cell Biology – Cytoskeleton and Trafficking

Du 10 juillet 2016 au 31 juillet 2016

Cajal School 2016 – Bordeaux Neurocampus

Development and plasticity of the nervous system critically depends on the neuronal cytoskeleton.
 The organization and dynamic remodeling of the neuronal cytoskeleton contributes to all morphological and functional changes in neurons, including migration, polarization, axon outgrowth, dendrite development and synapse formation. The neuronal cytoskeleton provides tracks for intracellular transport, sets up local cues to position organelles, acts as a signaling device and generates cellular forces that are fundamental to all aspects of neuronal function. Cytoskeleton remodeling and axonal trafficking have emerged as one of the most exciting and rapidly moving fields in cellular neurobiology. This field is experiencing a revolution in molecular, genetic and imaging technologies for analysing the dynamics of these processes during neuronal development and plasticity. The study of the molecular mechanisms of cytoskeletal dynamics and neuronal trafficking are also key to understanding what goes wrong in many neurodevelopmental and neurodegenerative diseases.

In this training course, we are excited to provide a forum to present the most recent findings in the field of neuronal cytoskeleton and trafficking, and provide advanced training to a new generation of neuroscientists. This will be achieved in three ways: 1) keynote lectures of world-renown experts in the neuronal cytoskeleton and trafficking field; 2) lectures by young investigators to provide knowledge to the participants about the latest developments in the field, including methodologies and; 3) experimental mini-projects.

The training course will focus on the following topics: cytoskeleton dynamics, axonal transport, growth cone migration, neuronal plasticity, synaptogenesis, neurodegeneration and regeneration.

Course directors

Casper Hoogenraad,
Utrecht University, NL.
Monica Sousa,
Olivier Thoumine,
University of Bordeaux, FR

Keynote Speakers

Vann Bennett, Duke University, USA
Pico Caroni, FMI, Switzerland
Valerie Castellani, Institut NeuroMyoGène, France
Carlos Dotti, KU Leuven, Belgium
James Fawcett, Cambridge University, UK
Volker Haucke, FMP Berlin, Germany
Christian Lohmann, Netherlands Institute for Neuroscience in Amsterdam, The Netherlands
Eva Mandelkow, Deutsches Zentrum für Neurodegenerative Erkrankungen, Germany
Villu Maricq, University of Utah, USA
Jeroen Pasterkamp, UMC Utrecht, The Netherlands
Jan Pielage, FMI, Switzerland
Matthijs Verhage, CNCR-VU, Amsterdam, The Netherlands
Rafael Yuste, Columbia University, USA

Adna Dumitrescu, UK
Alexandre Favereaux, Bordeaux, France
Andreas Prokop, Manchester, UK
Christophe Leterrier, Marseille, France
Corette Wierenga, Utrecht, the Netherlands
David Perrais, Bordeaux, France
Etienne Herzog, Bordeaux, France
Fernando Mar, Portugal
Gregory Giannone, Bordeaux, France
Harold MacGillavry, Utrecht, Netherlands
Julien Falk, Lyon, France
Laura Sayas, Spain
Lukas Kapitein, Utrecht, the Netherlands
Martin Harterink, Utrecht, the Netherlands
Martin Heine, Magdeburg, Germany
Mireille Montcouquiol, Bordeaux, France
Natalia Sanchez-Soriano, Liverpool, UK
Pirta Hotulainen, Helsinki, Finland
Sebastian Dupraz, Germany
Silvio Rizzoli, Germany
Vincent Studer, Bordeaux, France


Spine dynamics
Synapse formation
Axon outgrowth
Growth cone migration and guidance
Cytoskeleton in axons
Cytoskeleton organization in the axon initial segment
Neuronal polarity
Axonal and dendritic transport
Axon Degeneration
Axon Regeneration


Fee : 3.500 € (includes tuition fee, accommodation and meals)
The CAJAL Programme has limited funds available. 4 stipends (waived fee) are available per course. You can apply for a stipend inside the course general application form.
However, any applicant in need of a grant is encouraged to first request it from their lab, institution or government, if possible.
Access to the Bordeaux Imaging Center was supported through a partnership with France Bio Imaging


Last update: 6 septembre 2019