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X-WR-CALNAME:Bordeaux Neurocampus
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X-WR-CALDESC:Évènements pour Bordeaux Neurocampus
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DTSTART;TZID=Europe/Paris:20241217T110000
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DTSTAMP:20260410T160851
CREATED:20241101T185729Z
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UID:177067-1734433200-1734433200@www.bordeaux-neurocampus.fr
SUMMARY:Seminar - Lionel Dahan
DESCRIPTION:\nVenue: Centre Broca \n\nLionel Dahan\nCRCA\, Toulouse \nInvited by Nicolas Mallet \nTitle\nDopamine: a teaching signal triggering hippocampal long‑term potentiation and contextual learning \n\nAbstract\nLong term potentiation (LTP) is one of the mechanisms underlying learning and memory. However\, a hippocampus relying purely on Hebbian rules should encode every single event\, which does not seems to be the case. This led theoreticians to propose a NeoHebbian framework in which the conjunction between pre- and post-synaptic activity requires a third factor – a neuromodulator playing the role of a teaching signal – in order to trigger long lasting synaptic plasticity. We used electrophysiology\, optogenetics and behavior to show that VTA dopamine neurons innervating the hippocampus can operate as a teaching signal that triggers NeoHebbian LTP and promotes contextual learning. \n
URL:https://www.bordeaux-neurocampus.fr/event/seminar-lionel-dahan/
CATEGORIES:A la une,Pour les scientifiques,Séminaire Impromptu
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