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X-WR-CALNAME:Bordeaux Neurocampus
X-ORIGINAL-URL:https://www.bordeaux-neurocampus.fr
X-WR-CALDESC:Évènements pour Bordeaux Neurocampus
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TZID:Europe/Paris
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TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:CEST
DTSTART:20210328T010000
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TZOFFSETTO:+0100
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DTSTART:20211031T010000
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20210920
DTEND;VALUE=DATE:20211010
DTSTAMP:20260602T070236
CREATED:20191021T090540Z
LAST-MODIFIED:20211005T150111Z
UID:112223-1632096000-1633823999@www.bordeaux-neurocampus.fr
SUMMARY:Cajal lectures: Ageing cognition
DESCRIPTION:The lectures during the Cajal course are open to every member of Bordeaux Neurocampus. \nVenue: CGFB \n\nSeptember 20 – 2:00pm\nLuisa Lopes (iMM Lisboa\, Portugal)\nTowards assessing human synaptic aging – new models \nSeptember 21 – 9:00am (remotely)\nCheryl Grady (University of Toronto\, Canada)\nUsing neuroimaging to examine between-person and within-person variability in cognition across the adult lifespan \nSeptember 21 – 11:00am\nNora Abrous (Bordeaux Neurocampus\, France)\nRole of hippocampus neurogensis incognitive aging \nSeptember 22 – 9:00am\nCarol Barnes (University of Arizona\, USA)\nRegion-selective hippocampal contributions to altered cognition in aging \nSeptember 22 – 11:00am (remotely)\nMaria Llorens-Martin (Universidad Autonoma Madrid\, Spain)\nHuman adult hippocampal neurogenesis during physiological and pathological aging \nSeptember 24 – 9:00am\nLaure Rondi-Reig (Sorbonne University\, France)\nStudying Memory systems using navigation behavior \nSeptember 24 – 11:00\nAline Marighetto (Bordeaux Neurocampus\, France)\nAge-related decline of declarative memory: from temporal binding process to synaptic trafficking of hippocampal NMDA receptors \nSeptember 27 – 5:00pm (remotely)\nYaakov Stern (Columbia University\, USA)\nThe neural basis of cognitive reserve \nSeptember 30 – 11:00am (remotely)\nAdam Antebi (Max Plank Institute\, Germany)\nConvergent mechanisms of longevity \nOctober 4 – 9:00am\nLuc Buée (University of Lille\, France)\nAlzheimer’s disease: The amyloid cascade hypothesis from the tau side \nOctober 4 – 11:00am\nLars Nyberg (Umea University\, Sweden)\nStudies of « brain reserve »\, « cognitive reserve »\, and « brain maintenance » – and some thoughts on « resilience » \nOctober 5 – 9:00am (remotely)\nHélène Amieva (Bordeaux population health center\, France)\nTrajectories of cognitive ageing: lessons from population-based epidemiologic studies \nOctober 5 – 11:00am\nGwenaëlle Catheline (Bordeaux Neurocampus\, France)\nInter-individual variability in brain changes during aging : multimodal MRI-based studies in population based-cohorts \n\nhttp://www.bordeaux-school-of-neuroscience.eu/ \n  \n\nAbout the Cajal course\nVenue: Bordeaux School of Neuroscience \nThe normal aging process is associated with reduced performance on cognitive tasks that require one to quickly process or transform information to make a decision\, including measures of speed of processing\, executive cognitive function\, working and relational memories. Structural and functional alterations in the brain correlate with these age-related cognitive changes\, such as loss of synapses\, and dysfunction of neuronal networks. It is crucial to develop new approaches that consider the whole neuroanatomical\, endocrine\, immunological\, vascular and cellular changes impacting on cognition. \nThis 3-week course will cover the fundamentals of cognitive aging -including inter-individual differences\, cognitive and brain reserve and risk factors- and highlight the newest functional imaging methods to study human brain function. The Faculty will share the state-of-the-art molecular\, optical\, computational\, electrophysiological\, behavioural and epidemiological approaches available for studying the aging brain in diverse model systems. The Students will learn the potential and limitations of these methods\, through practical experience in a combination of lectures addressing aging in both humans and animal models and hands-on-projects. They will acquire sufficient practical experience to model\, design and interpret experiments and brainstorm on novel technologies and hypotheses to explore the aging of the brain using more integrative and creative approaches. \nCourse director\nLuísa Lopes\nNeurobiology of Ageing & Disease\niMM Lisboa\nPortugal \nCo-directors\nCheryl Grady\nThe Rotman Research Institute\, Baycrest\,\nCanada \nNora Abrous\nNeurocentre Magendie INSERM U 1215\,\nUniversity of Bordeaux\nFrance \nKeynote speakers\nHélène Amieva (Bordeaux Population Health\, France)\nAdam Antebi (Max Planck Institute for Biology of Ageing\, Germany)\nCarol Barnes (University of Arizona\, USA)\nLuc Buée (Centre de Recherche Jean-Pierre Aubert\, France)\nGwenaëlle Catheline (Bordeaux Neurocampus\, France)\nMaria Llorens (Centro de Biologia Molecular Severo Ochoa\, Spain)\nAline Marighetto (Bordeaux Neurocampus\, France)\nLars Nyberg (Umeå University\, Sweden)\nLaure Rondi-Reig (Sorbonne University\, France)\nYaakov Stern (Columbia University\, USA)\nTony Wyss-Coray (Stanford University\, USA) \nMore details\nhttp://cajal-training.org/on-site/ageing-cognition/ \n
URL:https://www.bordeaux-neurocampus.fr/event/cajal-course-ageing-cognition/
CATEGORIES:Cajal Lectures,Formations,not-calendar,Pour les scientifiques
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BEGIN:VEVENT
DTSTART;VALUE=DATE:20210922
DTEND;VALUE=DATE:20210925
DTSTAMP:20260602T070236
CREATED:20210603T124039Z
LAST-MODIFIED:20210922T163202Z
UID:135644-1632268800-1632527999@www.bordeaux-neurocampus.fr
SUMMARY:4th joint franco-british meeting of Neuroendocrinology
DESCRIPTION:Online \nOrganizing committee\n\n\nMarie-Pierre Moisan\, Nutrineuro\nMuriel Darnaudéry\, Nutrineuro\nXavier Fioramonti\, Nutrineuro\nDaniela Cota\, NeuroCentre Magendie\nPhilippe Ciofi \, NeuroCentre Magendie\n\n\nProgram\, registration\nhttps://bsn-sne2020.sciencesconf.org/ \n
URL:https://www.bordeaux-neurocampus.fr/event/4th-joint-franco-british-meeting-of-neuroendocrinology/
CATEGORIES:Pour les scientifiques,Symposiums
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20210924T090000
DTEND;TZID=Europe/Paris:20210924T103000
DTSTAMP:20260602T070236
CREATED:20210906T172309Z
LAST-MODIFIED:20210909T133247Z
UID:137887-1632474000-1632479400@www.bordeaux-neurocampus.fr
SUMMARY:Cajal lecture - Laure Rondi-Reig
DESCRIPTION:Venue: CGFB \n\nLaure Rondi-Reig\nSorbonne Université\, Paris\, France \nStudying Memory systems using navigation behavior \n
URL:https://www.bordeaux-neurocampus.fr/event/cajal-lecture-laure-rondi-reig-sorbonne-universite-paris-france/
CATEGORIES:Cajal Lectures,Pour les scientifiques
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BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20210924T110000
DTEND;TZID=Europe/Paris:20210924T123000
DTSTAMP:20260602T070236
CREATED:20210906T173105Z
LAST-MODIFIED:20210909T125443Z
UID:137901-1632481200-1632486600@www.bordeaux-neurocampus.fr
SUMMARY:Cajal lecture - Aline Marighetto
DESCRIPTION:Venue: CGFB \n\nAline Marighetto\nNeurocentre Magendie\, Bordeaux Neurocampus\, France \nAge-related decline of declarative memory: from temporal binding process to synaptic trafficking of hippocampal NMDA receptors \n
URL:https://www.bordeaux-neurocampus.fr/event/cajal-lecture-aline-marighetto/
CATEGORIES:Cajal Lectures,Pour les scientifiques
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20210924T113000
DTEND;TZID=Europe/Paris:20210924T123000
DTSTAMP:20260602T070236
CREATED:20210518T115521Z
LAST-MODIFIED:20210915T093413Z
UID:134960-1632483000-1632486600@www.bordeaux-neurocampus.fr
SUMMARY:Séminaire - Frédéric Checler
DESCRIPTION:\n	\n		\n			Venue: Centre Broca Nouvelle-Aquitaine \n\n\n		\n	\n\n	\n		\n			Title\nAlzheimer’s disease etiology: contribution of APP catabolites distinct from canonical Aβ \nAbstract\nAβ has long been at the gravity center of AD pathology. Thus\, the amyloid cascade predicts that Aβ accumulation corresponds to the etiological trigger of the disease. However\, most of clinical assays aimed at preventing Ab formation or neutralizing it after production have failed so far. We showed that besides Aβ\, APP-CTF fragments (namely C99) generated by an enzyme called b-secretase could well contribute to the pathology\, before any Ab detection and independently of Aβ. \nThis seminar will gather recent evidences from our laboratory concerning the early presence of C99 in brain\, its toxic phenotypes including endolysososmal perturbation and mitochondrial defects\, its occurrence in exosomal vesicles and a genetic approach aimed at lowering its production. This seminar will explain the deleterious side-effects observed when targeting g-secretase in vivo\, that could to some extent account for the drastic alterations observed in clinical trials. \nSelected publications\nLAURITZEN\, I .\, PARDOSSI-PIQUARD\, R.\, BAUER\, C.\, BRIGHAM\, E.\, ABRAHAM\, J.D.\, RANALDI\, S.\, FRASER\, P. St-GEORGE-HYSLOP\, P.\, LE THUC\, O.\, ESPIN\, V.\, CHAMI\, L.\, DUNYS\, J. and CHECLER\, F. (2012) The b-secretase-derived C-terminal fragment of b-APP\, C99 but not Ab\, is a key contributor to early intraneuronal lesions in triple transgenic mouse hippocampus. J. Neurosci. 32\, 16243-16255. \nlauritzen\, I.\,  PARDOSSI-PiQUARD\, R.\, BOURGEOIS\, A.\,PAGNOTTA\, S.\, BIFERI\, M-G.\, BARKATS\, M.\, LACOR\, P.\, KLEIN\, W.\, BAUER\, C. and CHECLER F (2016) Intraneuronal aggregation of the b-CTF fragment of APP (C99) induces Ab-independent lysosomal-autophagic pathology. Acta Neuropathol. 132\, 257-276. \nLAURITZEN\, I.\, BECOT\, A.\, BOURGEOIS\, A.\, PARDOSSI-PIQUARD\, R.\, BIFERI\, M-G.\, BARKATS\, M. and CHECLER F. (2019) Targeting g-secretase triggers the selective enrichment of oligomeric APP-CTFs in brain extracellular vesicles from Alzheimer cell and mouse models. Translational. Neurodeg. 8\, 35\, doi:10.1186/s40035-019-0176-6 \nVAILLANT-BEUCHOT\, L.\, MARY\, A.\, PARDOSSI-PIQUARD\, R.\, BOURGEOIS\, A.\, LAURITZEN\, I.\, EYSERT\, F.\, KINOSHITA\, P.F.\, CAZARETH\, J.\, BADOT\, C.\, FRAGAKI\, K.\, BUSSIERE\, R.\, MARTIN\, C.\, MARY\, R.\, BAUER\, C.\, PAGNOTTA\, S.\, PAQUIS-FLUCKLINGER\, V.\, BUEE-SCHERRER\, V.\, BUEE\, L.\, LACAS-GERVAIS\, S\, CHECLER F and CHAMI\, M. (2021) Accumulation of amyloid precursor protein C-terminal fragments triggers mitochondrial structure\, function and mitophagy defects in Alzheimer’s disease models and human brains . Acta Neuropathologica. 141\, 39-65. \n  \n\nInvited by Gaël Barthet and Christophe Mulle (IINS) \n\n		\n	\n\n	\n		\n			 \n\n		\n	\n\n	\n		\n			Frédéric Checler\n\nUniversité de Nice-Sophia-Antipolis\nInstitut de Pharmacologie Moléculaire et Cellulaire\, CNRS-UMR7275\,\nTeam labeled   « Fondation pour la Recherche Médicale »  et  « Laboratoire d’excellence Distalz »\nSophia-Antipolis\, France\n\nPage web\n\n		\n	\n\n
URL:https://www.bordeaux-neurocampus.fr/event/seminaire-frederic-checler/
CATEGORIES:A la une,Pour les scientifiques,Séminaire du vendredi
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