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X-WR-CALNAME:Bordeaux Neurocampus
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X-WR-CALDESC:Évènements pour Bordeaux Neurocampus
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DTSTART:20250330T010000
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DTSTART;TZID=Europe/Paris:20250709T110000
DTEND;TZID=Europe/Paris:20250709T110000
DTSTAMP:20260413T221714
CREATED:20250513T103251Z
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UID:183804-1752058800-1752058800@www.bordeaux-neurocampus.fr
SUMMARY:CANCELLED // Seminar - Hayder Amin
DESCRIPTION:This event has been cancelled \nVenue: Centre Broca \n\nHayder Amin\, PhD \nBiohybrid Neuroelectronics (BIONICS) Group\, German Center for Neurodegenerative Diseases (DZNE) \nhttps://www.dzne.de/en/research/research-areas/fundamental-research/research-groups/amin/research-areasfocus/ \nInvited by Muriel Koehl (Magendie) \nTitle\nMultiscale Computation and the Logic of Neural Ensembles Across States \nAbstract\nThe computational power of the brain emerges from the coordinated activity of neuronal ensembles\nembedded in complex\, multilayered circuits. While single-neuron approaches have provided\nfoundational insights\, they fail to capture the distributed\, dynamic structure of computation that\nunfolds across spatial and temporal scales. This is particularly true in circuits such as the hippocampus\nand olfactory bulb\, where plasticity\, sensory integration\, and experience-dependent reconfiguration\noccur on a systems level.\nIn this talk\, I will present our strategy to decode circuit-level computation using custom-engineered\nCMOS-based neuroelectronic platforms. These systems enable large-scale\, high-resolution recordings\nthat resolve cell assembly dynamics\, track long-term potentiation across layers\, and capture\nexperience-induced network-level plasticity. This multiscale approach allows us to go beyond the\nsingle-cell paradigm and examine the logic of computation embedded in functional ensembles and\ncircuit topology.\nImportantly\, we apply this framework to dissect how experience\, stress\, aging\, and disease reshape\nneural complexity — revealing distinct\, circuit-specific alterations in spatiotemporal dynamics. These\nchanges expose candidate biomarkers that reflect disruptions in information flow\, plasticity\, or\nensemble coordination. By linking computation\, architecture\, and dysfunction\, our work provides a\nscalable foundation for understanding how neural systems adapt — or fail — across physiological and\npathological states.\nBeyond fundamental neuroscience\, our research establishes a scalable foundation for advancing\nneurotechnology and brain-inspired AI. By combining high-resolution experimental access to circuit\ndynamics with computational modeling of multiscale activity patterns\, our approach enables more\nbiologically grounded theories of learning\, memory\, and adaptive computation. These insights inform\nthe design of next-generation interfaces\, synthetic neural systems\, and data-driven frameworks that\nmove toward functional emulation of brain-like complexity in both health and engineered systems. \n
URL:https://www.bordeaux-neurocampus.fr/event/seminar-hayern-amin/
CATEGORIES:A la une,Magendie,Pour les scientifiques,Séminaire Impromptu
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