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X-WR-CALNAME:Bordeaux Neurocampus
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DTSTART;TZID=Europe/Paris:20250926T113000
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UID:184085-1758886200-1758886200@www.bordeaux-neurocampus.fr
SUMMARY:Friday Seminar - Laura Corbit
DESCRIPTION:Venue: centre Broca \n\nLaura Corbit\nUniversity of Toronto \nInvited by Etienne Coutureau (INCIA) \nTitle\nDiet-induced changes to striatal circuitry and implications for behavioural control. \nAbstract\nHabits provide a rapid\, efficient means for decision making however\, this comes with a loss of behavioural flexibility.  Although striatal circuits control instrumental learning including habits\, little is known about how experiences that accelerate habit learning alter activity in these circuits to promote premature habitual control.  Using the outcome devaluation task to distinguish flexible actions from habits\, we have found that long-term access to an obesogenic diet promotes habitual behavioural control. I will present data that demonstrate changes inmicroglial activity following the obesogenic diet are largely observed in the dorsomedial striatum associated with goal-directed performance and that local inflammation in this region is sufficient to induce behavioural deficits. Importantly\, pharmacologically preventing to limiting microglial changes restored goal-directed control. These results have important implications for understanding failures of behavioural control and strategies for improving behavioural flexibility. \nBiosketch\nI received my PhD from UCLA where I worked with Bernard Balleine studying the neural circuits underlying goal-directed learning. I completed my postdoctoral training in the lab of Patricia Janak at the Ernest Gallo Clinic and Research Centre where I studied how exposure to alcohol altered behavioural control.  From there I moved to the School of Psychology at the University of Sydney where I was a Lecturer/Senior Lecturer until 2017 when I moved to the University of Toronto where I am currently a Professor in the Department of Psychology. \nMy lab continues to study the behavioural and neural control of instrumental learning and reward-seeking behaviours. We are particularly interested in the role of different types of behavioural control and how they are acquired\, as well as how life experiences such as diet or exposure to drugs alters learning and behaviour. \n
URL:https://www.bordeaux-neurocampus.fr/event/friday-seminar-laura-corbit/
CATEGORIES:A la une,INCIA,Pour les scientifiques,Séminaire du vendredi
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