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X-WR-CALNAME:Bordeaux Neurocampus
X-ORIGINAL-URL:https://www.bordeaux-neurocampus.fr
X-WR-CALDESC:Évènements pour Bordeaux Neurocampus
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DTSTART;TZID=Europe/Paris:20201204T113000
DTEND;TZID=Europe/Paris:20201204T123000
DTSTAMP:20260511T231036
CREATED:20200706T180500Z
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UID:123024-1607081400-1607085000@www.bordeaux-neurocampus.fr
SUMMARY:Monthly conference (PhD seminar series) - Jakob Balslev Sørensen
DESCRIPTION:Online.\nLink will be sent to Neurocampus mailing list.\nYou work at Bordeaux university? Send us a message to get the link. \n\nJakob Balslev Sørensen\nDepartment of Neuroscience\, \nUniversity of Copenhagen\, Blegdamsvej 3B\, 2200 Copenhagen\, Denmark.\nhttps://in.ku.dk/employees/?pure=en/persons/137549 \nUsing neuroendocrine cells to study the role of synaptotagmin-7 in vesicle priming and fusion.\nFusion of dense-core or synaptic vesicles with the plasma membrane is the final step in the exocytotic cascade leading to release of neurotransmitter and neuropeptides. The penultimate step is vesicle priming: the build-up of a fusion machinery between the vesicle and the plasma membrane. There is amble evidence that regulation of priming is a key element in presynaptic and secretory plasticity\, however distinguishing between vesicle priming and fusion is often difficult\, because typically only the final step (neurotransmitter release) is directly measured. Here\, I will discuss how we use adrenal chromaffin cells\, capacitance measurements\, calcium uncaging and 3D Electron Tomography to dissect effects on vesicle priming and fusion. I will show how we recently used this powerful system to describe the function of synaptotagmin-7 in vesicle priming and fusion. \n  \n\nInvited by Bordeaux Neurocampus and the NBA \n
URL:https://www.bordeaux-neurocampus.fr/event/conference-mensuelle-phd-seminar-decembre2020/
CATEGORIES:A la une,Conférences mensuelles,Pour les scientifiques
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