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X-WR-CALNAME:Bordeaux Neurocampus
X-ORIGINAL-URL:https://www.bordeaux-neurocampus.fr
X-WR-CALDESC:Évènements pour Bordeaux Neurocampus
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DTSTART:20260329T010000
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DTSTART:20261025T010000
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DTSTART;TZID=Europe/Paris:20260703T113000
DTEND;TZID=Europe/Paris:20260703T113000
DTSTAMP:20260724T030128
CREATED:20260616T142748Z
LAST-MODIFIED:20260618T090304Z
UID:203338-1783078200-1783078200@www.bordeaux-neurocampus.fr
SUMMARY:Seminar - James Olopade
DESCRIPTION:Venue: Centre Broca \n \n\nProf. James Olopade\nProfessor of Neuroscience and Comparative Anatomy\,\nHumboldt Research Hub for Zoonotic Arboviral Diseases (HRH-ZAD)\nUniversity of Ibadan (Nigeria) \nInvited by Marc Landry (IMN) \nTitle\nEnvironmental Pollution and the Brain: What have we Learnt from the Lab and the Field \nAbstract\nMy lab has been looking at environmental toxicants and how they affect the brain. In the last 2 decades\, we have concentrated on vanadium\, a transition metal that is a contaminant of the crude oil of many countries\, and an alloy used in the steel industry. The continuous global dependence on oil and thus subsequent increased exploration\, crude oil burning\, gas flaring\, and the increased demand for steel production make vanadium toxicity a pertinent issue. I shall be presenting on work done on the experimental neurotoxicity of vanadium and the neuro-therapeutics that we have explored. Also\, using the African Giant Rat as models in our lab in the last 15 years\, we have examined real-life changes in the brain in polluted areas in Nigeria. In addition\, however\, I shall also be sharing briefly on the good of vanadium in the nervous system and infectious viruses that have been seen in the brains of wild rodents in the course of my research. \n
URL:https://www.bordeaux-neurocampus.fr/event/seminar-james-olopade/
CATEGORIES:A la une,IMN,Pour les scientifiques,Séminaire Impromptu
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DTSTART;TZID=Europe/Paris:20260703T140000
DTEND;TZID=Europe/Paris:20260703T140000
DTSTAMP:20260724T030128
CREATED:20260605T115010Z
LAST-MODIFIED:20260616T165234Z
UID:202788-1783087200-1783087200@www.bordeaux-neurocampus.fr
SUMMARY:Seminar - Yoshiyuki Kubota
DESCRIPTION:Venue: CARF \n\nYoshiyuki KUBOTA\nNational Institute for Physiological Sciences\, Okazaki\, Japan \nInvited by Naoya Takahashi (IINS) \nTitle\nUnique Spatial Organization of Perisynaptic Astrocytic Processes in Layer 1 of the Primary Motor Cortex After Motor Skill Learning \nAbstract\nAstrocytes play a key role in regulating synaptic transmission as part of the tripartite synapse. Each astrocyte typically occupies a distinct\, non-overlapping domain. However\, the plasticity of these domains—especially during learning-related synaptic remodeling—remains largely unknown. Using two-photon imaging in Thy1-GFP mice trained for 8 days on a forelimb seed-reaching task\, we first identified dendritic segments of the apical tuft of a layer 5 pyramidal neuron that exhibited high spine turnover (Sohn et al.\, Science Advances\, 2022). Correlative light and electron microscopy using large-scale volume EM data collected from these mice with automated tape-collecting ultramicrotome and scanning electron microscopy revealed that these active dendritic segments were contacted by perisynaptic astrocytic processes (PAPs) originating from 3–6 distinct astrocytes\, which was analyzed quantitatively using our in house developed measurement methods. Notably\, these astrocytic processes extended directly and specifically toward each active dendritic segment. Despite the convergence of processes from multiple astrocytes at the level of dendritic segment\, individual dendritic spines were typically contacted by PAPs from only a single astrocyte\, indicating highly organized astrocyte-synapse interactions. In addition\, astrocyte cell bodies in layer 1 were arranged in a tiled pattern beneath the pia mater\, forming a sheet-like organization. This suggests that layer 1 astrocytes exhibit compartment-specific structural organization. \nTogether\, our findings suggest that astrocytic processes dynamically reorganize in an experience-dependent manner and may contribute to synapse-specific modulation during motor learning. Our EM-based analysis provides new insights into the fine-scale morphology of layer 1 astrocytes and their precise interactions with neurons. \n
URL:https://www.bordeaux-neurocampus.fr/event/seminar-yoshiyuki-kubota/
CATEGORIES:A la une,Pour les scientifiques,Séminaire Impromptu
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