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X-WR-CALNAME:Bordeaux Neurocampus
X-ORIGINAL-URL:https://www.bordeaux-neurocampus.fr
X-WR-CALDESC:Évènements pour Bordeaux Neurocampus
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DTSTART;VALUE=DATE:20221219
DTEND;VALUE=DATE:20230619
DTSTAMP:20260409T194906
CREATED:20221215T174158Z
LAST-MODIFIED:20230214T143012Z
UID:153784-1671408000-1687132799@www.bordeaux-neurocampus.fr
SUMMARY:Exposition: Illusions
DESCRIPTION:Lieu : Cap Siences \n\n\n\nEt si le cerveau était un véritable terrain de jeu… Qu’est-ce qu’une illusion ? Comment et pourquoi sommes-nous trompés ? \n\n\n\n\nSi l’illusion naît de nos sens\, elle s’élabore dans le cerveau. Nous voyons\, entendons\, touchons « avec notre cerveau ». Une perception est rarement uni-sensorielle. Plusieurs sens se combinent pour produire une interprétation du monde qui nous entoure : c’est le rôle du cerveau de produire du sens. Il utilise le passé pour s’adapter au présent et dans de nombreux cas compenser le manque d’informations dont il dispose. \nLe cerveau Il tient compte de ce qu’il “sent”\, mais aussi de ce qu’il sait déjà\, de ce que nous avons vécu\, mémorisé. Ce qui nous rend bien des services au quotidien pour prendre des décisions et réagir rapidement ! Mais aussi sophistiqué soit-il\, cet outil peut cependant être trompé par certaines situations… \nCette exposition\, propose une approche interactive à la découverte de nos sens et de nos perceptions. Les manipulations\, des plus simples aux plus impressionnantes troublent les perceptions dans une expérience déroutante. \n\n\n\n\nLe cerveau devient alors un terrain de jeu : Alors\, prêts pour une nouvelle expérience de la réalité ? \n  \n\n\n
URL:https://www.bordeaux-neurocampus.fr/event/exposition-illusions/
CATEGORIES:Evénements pour tous,not-calendar,Semaine du cerveau 2023
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DTSTART;TZID=Europe/Paris:20230505T113000
DTEND;TZID=Europe/Paris:20230505T113000
DTSTAMP:20260409T194906
CREATED:20230213T160637Z
LAST-MODIFIED:20230503T163925Z
UID:155551-1683286200-1683286200@www.bordeaux-neurocampus.fr
SUMMARY:Seminar - Alexandre Charlet
DESCRIPTION:Venue: Centre Broca Nouvelle-Aquitaine \n\nAlexandre Charlet\nINCI (Institut des Neurosciences Cellulaires et Intégratives)\, Strasbourg\nhttps://inci.u-strasbg.fr/?page_id=5135\n \nInvited by Aude Panatier (Neurocentre Magendie) \nTitle\nOxytocin\, astrocytes and amygdala: a triptych for emotional adaptation? \nAbstract\nOur daily life is a succession of cognitive actions influenced by our emotions. Emotions\, often referred to as feelings\, are necessary to maintain a balance throughout the life of an individual\, if not his survival: love\, anger\, pain and fear are the most common examples. While neuronal networks sustaining emotions are well studied\, a tremendous question persists: how does our brain cellular networks supports the enduring effects of emotions? \nConsiderable evidence support a role for neuropeptides in the control of emotions in mammals. Oxytocin\, a nonapeptide mainly synthesized in the hypothalamus\, recently became a centre of attention for the regulation of affective behaviours. Particularly\, oxytocin-induced fear and anxiety regulations take place within the amygdala\, a key nucleus in processing of emotions in both physiological and pathological conditions. Despite these advances\, we still lack evidence on how neuropeptidergic systems support the plasticity of emotions processing throughout a lifetime. Interestingly\, alterations in glial cells might be linked to emotional impairments and adaptation\, particularly within the amygdala brain region. While major studies demonstrated over the last years a role for astrocytes in functional cellular networks modulation\, illustrated in memory and anxiety processing\, the contribution of astrocytes in the neuromodulatory effects of a neuropeptide has rarely been explored. We recently demonstrated that a subpopulation of the central amygdala astrocytes express the G-protein coupled oxytocin receptor\, and thus that oxytocin can tune astro-neuronal networks activity to control amygdala-related behaviour. \nThis work paves the way to our ongoing projects\, for which I hypothesize that astrocytes and neurons fulfil synergistic functions achieved at differential time points to support behavioral adaptation – a hypothesis I will explore and discuss during this Bordeaux Neurocampus conference. \nSelected publications\n#Corresponding and senior authors; *Co-first authors \nResearch articles in peer-reviewed journals \nIwasaki M*\, Lefevre A*\, Althammer F*\, Clauss Creusot E*\, Lapies O\, Petitjean H\, Hilfiger L\, Kerspern D\, Melchior M\, Küppers S\, Krablicher Q\, Patwell R\, Kania A\, Gruber T\, Kirchner MK\, Wimmer M\, Frohlich H\, Dotsch L\, Schimmer J\, Herpertz SC\, Ditzen B\, Schaaf CP\, Schoenig K\, Bartsch D\, Gugula A\, Trenk A\, Blasiak A\, Stern JE\, Darbon P\, Grinevich V#\, Charlet A#. An analgesic pathway from parvocellular oxytocin neurons to the periaqueductal gray in rats (Nature Communication\, in press). \nBaudon A*\, Clauss–Creusot E*\, F Althammer\, Charlet A. (2022). Emerging role for astrocytes in oxytocin-based modulation of brain circuits and functions. Progress in Neurobiology\, 217:102328. Review. \nWahis J*\, Baudon A*\, Althammer F*\, Kerspern D*\, Goyon S\, Hagiwara D\, Lefèvre A\, Barteczko L\, Boury-Jamot B\, Bellanger B\, Abatis M\, Silva da Gouveia M\, Benusiglio D\, Eliava M\, Rozov A\, Weinsanto I\, Knobloch-Bollmann HS\, Kirchner MK\, Roy RJ\, Wang H\, Pertin M\, Inquimbert P\, Pitzer C\, Siemens J\, Goumon Y\, Boutrel B\, Lamy CM\, Décosterd I\, Chatton J-Y\, Rouach N\, Young SW\, Stern JE\, Poisbeau P\, Stoop R\, Darbon P\, Grinevich V#\, Charlet A#. (2021) Astrocytes mediate the effect of oxytocin in the central amygdala on neuronal activity and affective states in rodents. Nature Neuroscience 24(4):529-541. \nTang Y*\, Benusiglio D*\, Lefevre A*\, Hilfiger L*\, Althammer F\, Bludau A\, Hagiwara D\, Baudon A\, Darbon P\, Schimmer J\, Kirchner MK\, Roy RK\, Wang S\, Eliava M\, Wagner S\, Oberhuber M\, Conzelmann KK\, Schwarz M\, Stern JE\, Leng G\, Neumann ID\, Charlet A#\, Grinevich V#. (2020) Social touch promotes inter-female communication via activation of parvocellular oxytocin neurons. Nature Neuroscience23(9):1125-1137. \nHilfiger L\, Zhao Q\, Kerspern D\, Inquimbert P\, Andry V\, Goumon Y\, Darbon P\, Hibert M\, Charlet A#. (2020) A Nonpeptide Oxytocin Receptor Agonist for a Durable Relief of Inflammatory Pain. Scientific Report\,10(1):3017. \n
URL:https://www.bordeaux-neurocampus.fr/event/seminar-alexandre-charlet/
CATEGORIES:A la une,Pour les scientifiques,Séminaire du vendredi
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