BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Bordeaux Neurocampus - ECPv4.9.10//NONSGML v1.0//EN
CALSCALE:GREGORIAN
METHOD:PUBLISH
X-WR-CALNAME:Bordeaux Neurocampus
X-ORIGINAL-URL:https://www.bordeaux-neurocampus.fr
X-WR-CALDESC:Évènements pour Bordeaux Neurocampus
BEGIN:VTIMEZONE
TZID:Europe/Paris
BEGIN:DAYLIGHT
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:CEST
DTSTART:20220327T010000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:CET
DTSTART:20221030T010000
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20221104T100000
DTEND;TZID=Europe/Paris:20221104T100000
DTSTAMP:20260421T205541
CREATED:20220921T084258Z
LAST-MODIFIED:20220921T134747Z
UID:151047-1667556000-1667556000@www.bordeaux-neurocampus.fr
SUMMARY:Seminar - Raphael Lamprecht
DESCRIPTION:Raphael Lamprecht\nSalle Purkinje (Centre Broca Nouvelle-Aquitaine) \n\nRaphael Lamprecht\nSagol Department of Neurobiology\, University of Haifa\, Haifa\, Israel \nInvited by Daniel Choquet (IINS) \nTitle\nThe roles of EphB2 and ephrinB2 in long-term memory formation \nAbstract\nEph receptors and their cognate ephrin ligands can signal in a bidirectional fashion between two opposing cells. They are attractive candidates to play a central role in memory formation as they are involved in the regulation of synaptic transmission and neuronal morphogenesis. We aim to explore the roles of EphB2 and ephrinB2 signaling in memory formation and enhancement. We found that activation of EphB2\, using a novel technology termed optoEphB2 that allows the control of EphB2 forward signaling activity by light\, enhances memory and that mice that express EphB2 that lacks forward signaling are impaired in the ability to form long-term memory. To explore the roles of ephrinB2 in memory we depleted ephrinB2 in different cell populations in the brain and studied the effect on the ability of the mice to form long-term memory. We revealed that ephrinB2 in different cell populations is essential for long-term memory formation. We also provide evidence for downstream molecular signaling pathways that can mediate EphB2 and ephrinB2 functions in memory formation. \n
URL:https://www.bordeaux-neurocampus.fr/event/seminar-raphael-lamprecht/
CATEGORIES:A la une,Pour les scientifiques,Séminaire Impromptu
END:VEVENT
END:VCALENDAR