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DTSTART:20190331T010000
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DTSTART:20191027T010000
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DTSTART;TZID=Europe/Paris:20190617T113000
DTEND;TZID=Europe/Paris:20190617T113000
DTSTAMP:20260430T231651
CREATED:20190521T140656Z
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UID:107755-1560771000-1560771000@www.bordeaux-neurocampus.fr
SUMMARY:Séminaire - Tomonori Takeuchi
DESCRIPTION:Lieu : Centre Broca Nouvelle-Aquitaine \n\nTomonori Takeuchi\, Associate Professor \nDepartment of Biomedicine\,\nThe Danish Research Institute of Translational Neuroscience (DANDRITE)\,\nAarhus Institute of Advanced Studies\,\nAarhus University\,\nDenmark\nhttp://dandrite.au.dk/people/team-leaders/tomonori-takeuchi/ \nInvité par Valentin Nägerl\, IINS \n\nAbstract:\nMany people have vivid memories of the first dinner date with their partner\, including details like the name of the restaurant and the food they had. In contrast\, it is very difficult to remember what you had for dinner a few weeks ago. Most everyday memories may be formed automatically in the hippocampus. The key role of this memory system is to filter out unnecessary information\, but keep the important memories by a mechanism that involves novelty-associated dopamine release in the hippocampus. Recently\, our studies (Takeuchi et al.\, Nature\, 2016) revealed that projections from neurons in the locus coeruleus to the hippocampus can drive novelty-associated enhancement of memory retention through non-canonical release of dopamine in the hippocampus\, in line with the synaptic tagging and capture theory of initial memory consolidation. These studies also raise a possibility that the impact of distinct novel experiences which\, by their very nature\, bear minimal relationship to past experiences (‘distinct novelty’) may differ from novel experiences that share some commonality with past experiences (‘common novelty’) (Yamasaki and Takeuchi\, Neural Plasticity\, 2017; Duszkiewicz et al.\, Trends Neurosci\, 2019). We now propose that memory of events accompanied by novelty can be selectively retained through two distinct dopaminergic mechanisms\, depending on the nature of the novel experience itself. \n
URL:https://www.bordeaux-neurocampus.fr/event/seminaire-impromptu-tomonori-takeuchi/
CATEGORIES:A la une,Pour les scientifiques,Séminaire Impromptu
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