{"id":198630,"date":"2026-06-04T10:02:29","date_gmt":"2026-06-04T08:02:29","guid":{"rendered":"https:\/\/www.bordeaux-neurocampus.fr\/?p=198630"},"modified":"2026-06-11T18:02:36","modified_gmt":"2026-06-11T16:02:36","slug":"boosting-biological-imaging-in-bordeaux","status":"publish","type":"post","link":"https:\/\/www.bordeaux-neurocampus.fr\/en\/boosting-biological-imaging-in-bordeaux\/","title":{"rendered":"Boosting Biological Imaging in Bordeaux"},"content":{"rendered":"

Source : communiqu\u00e9 du CNRS<\/strong><\/a><\/p>\n

\n

The Nouvelle-Aquitaine Region and the European Union, through the European Regional Development Fund (FEDER, for “Fonds Europ\u00e9en de D\u00e9veloppement R\u00e9gional”), are supporting two flagship projects led by the Interdisciplinary Institute of Neurosciences (IINS) and the Bordeaux Imaging Center (BIC). With nearly \u20ac3 million in FEDER funding \u2014 in addition to investments already secured under France 2030 and the State-Region Planning Contract (CPER, for “Contrat de Plan \u00c9tat-R\u00e9gion”) \u2014 a total of nearly \u20ac5 million will be invested in imaging infrastructure for the Bordeaux scientific community. This exceptional effort will further strengthen one of Europe’s leading centers in the field of life science imaging.<\/strong><\/p>\n

\"\"<\/a>
The architecture of the project<\/figcaption><\/figure>\n

Bordeaux is internationally recognized for its expertise in advanced biological imaging. The teams at the Interdisciplinary Institute of Neurosciences[1]<\/a> and the Bordeaux Imaging Center[2]<\/a>, two units of Bordeaux Neurocampus, are among the leading players in the development and use of cutting-edge imaging technologies for the study of living organisms. The BIC is also a founding member of France BioImaging and Euro-BioImaging, the leading national and European infrastructures in biological imaging, which bring together and coordinate the major platforms in the field.<\/p>\n

This momentum has recently been further strengthened\u00a0by the selection of two major projects under the Nouvelle-Aquitaine FEDER programme[3]<\/a>: MINFLUX and IMPACT. The CNRS is responsible for the administrative management of these projects.<\/p>\n

The MINFLUX project, led by IINS, will enable the acquisition of the first MINFLUX microscope to be installed in France and south-west Europe.<\/strong> The MINFLUX system represents a major technological breakthrough in photonic imaging and will be installed at the BIC. Developed from the work of Stefan Hell, winner of the 2014 Nobel Prize in Chemistry, this revolutionary technology achieves a localisation accuracy of 1 to 2 nanometres and enables the tracking of individual proteins at over 1,000 locations per second, bridging the gap between optical microscopy and structural biology. For the first time, it enables the direct observation of individual proteins with sufficient precision and speed to resolve their conformational changes, dynamic interactions and molecular architecture, capabilities unattainable by any other optical approach. Thanks to this unique equipment, Bordeaux, with the support of the Nouvelle-Aquitaine Region, will become a reference centre for this technology at both national and European level.<\/p>\n

The IMPACT project, meanwhile, will equip the BIC with a new generation of multiphoton imaging tools<\/strong>, enabling the observation of molecular interactions within thick living tissue with unprecedented precision and depth of analysis. This infrastructure will open up new opportunities in fields as diverse as neuroscience, cell biology, microbiology, plant biology, oncology and health biotechnology.<\/p>\n

These investments also include the deployment of new high-performance computing and storage infrastructure, which is essential for processing, analysing and utilising the massive volumes of data generated by these next-generation imaging technologies.<\/p>\n

This new equipment complements the investments already committed under France 2030, the State-Region Planning Contract and several major national and European programmes. In total, nearly \u20ac5 million will be allocated to strengthening the optical and electronic imaging capabilities of the local scientific community.<\/strong><\/p>\n

Beyond their scientific impact, these investments will have a major positive effect on the entire regional ecosystem. They will help to make Nouvelle-Aquitaine more attractive to researchers, students and innovative businesses, strengthen collaborations with industry partners, and develop new training programmes in cutting-edge technologies.<\/p>\n

The ambition is to offer the academic and industrial community one of the most advanced technological environments in Europe, capable of observing biological phenomena at all scales, from the living organism down to the individual molecule.
\nThanks to these investments, Bordeaux is consolidating its position amongst the major international centres for life imaging and equipping itself to accelerate the scientific discoveries and innovations of tomorrow.<\/p>\n

\"\"<\/a>
A. MINFLUX tracking at 1 kHz of a single protein in a living cell. Integrins, adhesion proteins, transiently localize within cellular adhesion structures (shown in grey with a dotted outline) and rapidly diffuse outside. Collaboration between the G. Giannone group (IINS), the D. M\u00fcller group (ETH Zurich) and J. Casares Arias (ETH Zurich Single Cell Facility). B. Observation of the cytoskeletal proteins \u03b2II- and \u03b2III-spectrins using MINFLUX microscopy in 3D two-colour mode. Left and top right: diagrams of the molecular organisation of \u03b2II- and \u03b2III-spectrins within the periodic cytoskeletal network of dendrites, shown in the xyz and xz planes respectively. Centre and bottom right: examples of images obtained with the microscope in the different planes. Collaboration: A. Brachet, Marie-Lise Jobin (IINS), Isabelle Jansen and Evelyn Garlick (Abberior).<\/figcaption><\/figure>\n

 <\/p>\n

[1]<\/a> IINS (CNRS\/Universit\u00e9 de Bordeaux)<\/p>\n

[2]<\/a> BIC (CNRS\/Inserm\/Universit\u00e9 de Bordeaux)<\/p>\n

[3]<\/a> Le FEDER (Fonds Europ\u00e9en de D\u00e9veloppement R\u00e9gional) est un outil de la politique de coh\u00e9sion europ\u00e9enne qui vise \u00e0 r\u00e9duire les \u00e9carts entre les r\u00e9gions europ\u00e9ennes.<\/p>\n

Contacts<\/strong><\/h3>\n

Bordeaux Imaging Center (BIC)
\n<\/strong>Daniel Choquet, directeur du BIC et coordinateur du projet IMPACT – daniel.choquet@u-bordeaux.fr<\/a>
\nChristel Poujol, responsable du p\u00f4le photonique du BIC et co-coordinatrice du projet IMPACT – christel.poujol@u-bordeaux.fr<\/a><\/p>\n

Institut Interdisciplinaire de Neurosciences (IINS)
\n<\/strong>Gr\u00e9gory Giannone, responsable d\u2019\u00e9quipe \u00e0 l\u2019IINS et coordinateur du projet MINFLUX – gregory.giannone@u-bordeaux.fr<\/a>
\nAnna Brachet et Olivier Rossier, Chercheurs \u00e0 l\u2019IINS et co-coordinateurs du projet MINFLUX – anna.brachet@u-bordeaux.fr<\/a>, olivier.rossier@u-bordeaux.fr<\/a><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Soutien de 2 projets au BIC et \u00e0 l’IINS par la R\u00e9gion Nouvelle-Aquitaine et l\u2019Union europ\u00e9enne, \u00e0 travers le Fonds FEDER.<\/p>\n","protected":false},"author":357,"featured_media":198629,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[759,133,770,443],"tags":[],"class_list":["post-198630","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-bic-en","category-fundings","category-iins-en","category-innovation-en"],"_links":{"self":[{"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/posts\/198630","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/users\/357"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/comments?post=198630"}],"version-history":[{"count":5,"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/posts\/198630\/revisions"}],"predecessor-version":[{"id":203039,"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/posts\/198630\/revisions\/203039"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/media\/198629"}],"wp:attachment":[{"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/media?parent=198630"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/categories?post=198630"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/tags?post=198630"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}