{"id":198115,"date":"2026-05-07T10:25:49","date_gmt":"2026-05-07T08:25:49","guid":{"rendered":"https:\/\/www.bordeaux-neurocampus.fr\/?p=198115"},"modified":"2026-05-07T10:28:23","modified_gmt":"2026-05-07T08:28:23","slug":"why-can-gentle-touch-be-harder-to-perceive-in-autism","status":"publish","type":"post","link":"https:\/\/www.bordeaux-neurocampus.fr\/en\/why-can-gentle-touch-be-harder-to-perceive-in-autism\/","title":{"rendered":"Why can gentle touch be harder to perceive in autism?"},"content":{"rendered":"

Andreas Frick’s team, from Neurocentre Magendie, has published a new article in Advanced Science.<\/em><\/p>\n

Comment<\/h3>\n

Our study offers a new step toward understanding tactile hyposensitivity in autism. Using a translational perceptual task in Fmr1\u2212\/y mice, we found impaired detection of faint tactile stimuli in a subgroup of animals. This hyposensitivity was associated with a reduced cortical signal-to-noise ratio, weaker sensory encoding, and disrupted ensemble dynamics in the primary somatosensory cortex. Strikingly, lowering neuronal excitability improves both encoding and tactile perception. This work provides a translational framework for probing neuronal-perceptual changes in neurodevelopmental conditions, reveals inter-individual variability in preclinical models, and uncovers the neural basis of tactile hyposensitivity in autism.<\/p>\n

\"\"<\/a><\/p>\n

Reference<\/h3>\n

Diminished Signal\u2010to\u2010Noise Ratio Disrupts Somatosensory Population Encoding and Drives Tactile Hyposensitivity in the Fmr1\u2212\/y Autism Model<\/em><\/strong>
\n<\/a><\/strong>Ourania Semelidou, Th\u00e9o Gauvrit, C\u00e9lien Vandromme, Alexandre Cornier, Anna Saint\u2010Jean, Yves Le Feuvre, Melanie Ginger, Andreas Frick
\nAdvanced Science<\/em>. 2026-04-15<\/span><\/a>
\n10.1002\/advs.202519479<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Ourania Semelidou et al in Advanced Science.<\/p>\n","protected":false},"author":108,"featured_media":198139,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-198115","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news-neurocampus"],"_links":{"self":[{"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/posts\/198115","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/users\/108"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/comments?post=198115"}],"version-history":[{"count":2,"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/posts\/198115\/revisions"}],"predecessor-version":[{"id":198141,"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/posts\/198115\/revisions\/198141"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/media\/198139"}],"wp:attachment":[{"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/media?parent=198115"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/categories?post=198115"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/tags?post=198115"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}