{"id":189612,"date":"2025-11-12T15:15:46","date_gmt":"2025-11-12T14:15:46","guid":{"rendered":"https:\/\/www.bordeaux-neurocampus.fr\/?p=189612"},"modified":"2025-11-27T10:16:58","modified_gmt":"2025-11-27T09:16:58","slug":"new-team-nomad-led-by-agnes-nadjar-at-imn","status":"publish","type":"post","link":"https:\/\/www.bordeaux-neurocampus.fr\/en\/new-team-nomad-led-by-agnes-nadjar-at-imn\/","title":{"rendered":"The NOMAD team, led by Agn\u00e8s Nadjar, is joining the IMN"},"content":{"rendered":"<p data-start=\"53\" data-end=\"330\"><strong data-start=\"53\" data-end=\"185\">The IMN welcomes a new team, NOMAD (Neuroimmunology of Metabolic Health and Disease), led by Agn\u00e8s Nadjar, since September 2025.<img loading=\"lazy\" decoding=\"async\" class=\"alignright wp-image-188973\" src=\"https:\/\/cdn-neurocampus.onlc.eu\/wp-content\/uploads\/2018\/07\/nadjar-agnes-DSC_0088-P-270x360.jpg\" alt=\"\" width=\"250\" height=\"333\" srcset=\"https:\/\/www.bordeaux-neurocampus.fr\/wp-content\/uploads\/2018\/07\/nadjar-agnes-DSC_0088-P-270x360.jpg 270w, https:\/\/www.bordeaux-neurocampus.fr\/wp-content\/uploads\/2018\/07\/nadjar-agnes-DSC_0088-P-578x770.jpg 578w, https:\/\/www.bordeaux-neurocampus.fr\/wp-content\/uploads\/2018\/07\/nadjar-agnes-DSC_0088-P.jpg 600w\" sizes=\"auto, (max-width: 250px) 100vw, 250px\" \/><\/strong><br data-start=\"185\" data-end=\"188\" \/>The team focuses on the communication between the immune system and the central nervous system, both under normal and pathological conditions.<\/p>\n<p data-start=\"337\" data-end=\"354\">Interview<\/p>\n<p data-start=\"356\" data-end=\"453\"><strong data-start=\"356\" data-end=\"376\">Claire Delattre: Could you tell us about your background and the different roles you\u2019ve held?<\/strong><\/p>\n<p data-start=\"455\" data-end=\"1350\"><strong data-start=\"455\" data-end=\"472\">Agn\u00e8s Nadjar:<\/strong> I was appointed as a lecturer at the University of Bordeaux in 2006 within the PsyNuGen unit. In 2009\u20132010, I had the opportunity to spend two years in Boston as a visiting scholar at Tufts University. Upon returning from the United States, I joined the NutriNeuro laboratory, where I stayed for ten years before joining the \u201cEnergy Balance and Obesity\u201d team at the Neurocentre Magendie. In September 2025, I had the opportunity to create my own research team within the Institute of Neurodegenerative Diseases: <em data-start=\"985\" data-end=\"1045\">\u201cNeuroimmunology of Metabolic Health and Disease\u201d (NOMAD).<\/em><br data-start=\"1045\" data-end=\"1048\" \/>In parallel, I was the coordinator of the <em data-start=\"1090\" data-end=\"1101\">Neurasmus<\/em> Master\u2019s program\u2014an elite European Master\u2019s in Neuroscience\u2014from 2014 to 2022 (now managed by Pascal Fossat). Since 2022, I have been the director of the EUR Neurosciences graduate school and, since 2024, the co-director of the SVS doctoral school.<\/p>\n<p data-start=\"1357\" data-end=\"1403\"><strong data-start=\"1357\" data-end=\"1403\">How do you feel about being a team leader?<\/strong><\/p>\n<p data-start=\"1405\" data-end=\"1995\">I seized this opportunity despite some apprehension regarding the responsibilities it entails, both scientifically and administratively. It also meant relaunching our research activity in a new environment, with its own culture and practices. But I was attracted by the challenge and felt ready to take it on\u2014especially in this laboratory, where I feel confident and well supported. I actually spent two years as a postdoctoral researcher at the IMN twenty years ago, and the collaborative spirit that prevails here still means a lot to me. Coming back as a team leader is truly a pleasure.<\/p>\n<p data-start=\"2002\" data-end=\"2052\"><strong data-start=\"2002\" data-end=\"2052\">Could you tell us about your research project?<\/strong><\/p>\n<p data-start=\"2054\" data-end=\"2772\">I have always been interested in neuroimmune interactions and how they are modulated by the environment. Today, my team studies how immune cells in the brain\u2014microglia and meningeal immunity\u2014regulate energy metabolism, with the goal of harnessing these mechanisms to prevent or slow down neurodegenerative diseases such as Alzheimer\u2019s, which are accompanied by profound metabolic disturbances.<br data-start=\"2447\" data-end=\"2450\" \/>An important aspect of our work focuses on the sexual dimorphism of these responses.<br data-start=\"2538\" data-end=\"2541\" \/>For me, the IMN\u2019s balance between fundamental research and clinical orientation is ideal: it allows us to anchor our projects in the context of neurodegenerative diseases while maintaining a translational perspective toward humans.<\/p>\n<p data-start=\"2779\" data-end=\"2848\"><strong data-start=\"2779\" data-end=\"2848\">What are your team\u2019s strengths, and what do you bring to the IMN?<\/strong><\/p>\n<p data-start=\"2850\" data-end=\"3166\">We strengthen IMN\u2019s research in neuroimmunology and glial cell biology\u2014fields that are relevant to many of the institute\u2019s physiopathological research areas. These concepts foster exchange and collaboration among the various teams on site. Together, we can learn from each other and help advance research at the IMN.<\/p>\n<p data-start=\"3173\" data-end=\"3313\"><strong data-start=\"3173\" data-end=\"3313\">You\u2019re the first woman to lead a team independently at the IMN. How do you feel about that? And your team happens to be entirely female.<\/strong><\/p>\n<p data-start=\"3315\" data-end=\"4003\">I joined the IMN because of my scientific background, not my gender (at least I hope so!). That said, if my presence contributes to increasing the representation of women in science and at the IMN, that\u2019s a very good thing. And if it shows young female researchers that it\u2019s possible to take on leadership positions as a woman, that\u2019s even better.<br data-start=\"3662\" data-end=\"3665\" \/>As for my team, the fact that it\u2019s entirely female is pure coincidence. Each member was chosen for her skills and expertise, not her gender. That said, the numbers speak for themselves: most students in the Neuroscience Master\u2019s program\u2014at least in Bordeaux\u2014are women. It\u2019s mainly in leadership positions that their presence remains rare.<\/p>\n<p data-start=\"4010\" data-end=\"4044\"><strong data-start=\"4010\" data-end=\"4044\">Could you introduce your team?<img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-188981 alignright\" src=\"https:\/\/cdn-neurocampus.onlc.eu\/wp-content\/uploads\/2025\/09\/nadjar-team-DSC_0082-360x240.jpg\" alt=\"\" width=\"360\" height=\"240\" srcset=\"https:\/\/www.bordeaux-neurocampus.fr\/wp-content\/uploads\/2025\/09\/nadjar-team-DSC_0082-360x240.jpg 360w, https:\/\/www.bordeaux-neurocampus.fr\/wp-content\/uploads\/2025\/09\/nadjar-team-DSC_0082-770x513.jpg 770w, https:\/\/www.bordeaux-neurocampus.fr\/wp-content\/uploads\/2025\/09\/nadjar-team-DSC_0082-136x91.jpg 136w, https:\/\/www.bordeaux-neurocampus.fr\/wp-content\/uploads\/2025\/09\/nadjar-team-DSC_0082-768x511.jpg 768w, https:\/\/www.bordeaux-neurocampus.fr\/wp-content\/uploads\/2025\/09\/nadjar-team-DSC_0082-1170x779.jpg 1170w, https:\/\/www.bordeaux-neurocampus.fr\/wp-content\/uploads\/2025\/09\/nadjar-team-DSC_0082-640x426.jpg 640w, https:\/\/www.bordeaux-neurocampus.fr\/wp-content\/uploads\/2025\/09\/nadjar-team-DSC_0082.jpg 1200w\" sizes=\"auto, (max-width: 360px) 100vw, 360px\" \/><\/strong><\/p>\n<p data-start=\"4046\" data-end=\"4614\">As of today, the NOMAD team is composed of two PhD students, <strong data-start=\"4107\" data-end=\"4125\">Giulia Cutugno<\/strong> and <strong data-start=\"4130\" data-end=\"4150\">Evita Kyriakidou<\/strong>, and a research engineer, <strong data-start=\"4177\" data-end=\"4194\">Jeanne Vergne<\/strong>.<br data-start=\"4195\" data-end=\"4198\" \/>Giulia and Evita are both recipients of <strong data-start=\"4238\" data-end=\"4265\">Marie Curie fellowships<\/strong> (MSCA Doctoral Network program), while Jeanne was hired for two years on an <strong data-start=\"4342\" data-end=\"4359\">Eranet NEURON<\/strong> project.<br data-start=\"4368\" data-end=\"4371\" \/>Starting next February, we will welcome <strong data-start=\"4411\" data-end=\"4426\">Jade Thomas<\/strong>, a Master\u2019s student from Bordeaux\u2019s <em data-start=\"4463\" data-end=\"4473\">NeuroBIM<\/em> program, and <strong data-start=\"4487\" data-end=\"4502\">Lou Taussac<\/strong>, a professional Bachelor\u2019s student from Toulouse. They will both be with us for six months.<br data-start=\"4594\" data-end=\"4597\" \/>More women again!<\/p>\n<h3>Contact<\/h3>\n<p>Agn\u00e8s Nadjar : <a class=\"mail-link\" data-enc-email=\"ntarf.anqwne[at]h-obeqrnhk.se\" data-wpel-link=\"ignore\"><span id=\"wpmt-611739-690697\">agnes.nadjar@u-bordeaux.fr<\/span><\/a><br \/>\nCentre Broca Nouvelle-Aquitaine<br \/>\n3rd floor &#8211; Office 364<\/p>\n<h3>Selected publications<\/h3>\n<ul class=\"wpv-loop js-wpv-loop\">\n<li class=\"PubsList\"><a class=\"\" title=\"Isolation of Hypothalamic Microglia from Freshly Perfused Adult Mouse Brain by Magnetic-Activated Cell Sorting\" href=\"http:\/\/www.doi.org\/10.3791\/66769\" target=\"_blank\" rel=\"noopener\"><span class=\"titrePub\">Isolation of Hypothalamic Microglia from Freshly Perfused Adult Mouse Brain by Magnetic-Activated Cell Sorting<\/span><br \/>\n<strong>Evangelia Kyriakidou, Giulia Cutugno<\/strong>, Camille Allard, <strong>Agnes Nadjar<\/strong>.<br \/>\n<em> JoVE<\/em>. 2024-09-06. (211)<br \/>\nDOI: 10.3791\/66769<\/a><\/li>\n<li class=\"PubsList\"><a class=\"\" title=\"Rethinking the role of microglia in obesity\" href=\"http:\/\/www.doi.org\/10.1016\/j.neuropharm.2024.109951\" target=\"_blank\" rel=\"noopener\"> <span class=\"titrePub\">Rethinking the role of microglia in obesity<\/span><br \/>\n<strong>G. Cutugno<\/strong>, <strong>E. Kyriakidou<\/strong>, <strong>A. Nadjar.<\/strong><br \/>\n<em> Neuropharmacology<\/em>. 2024-04-01. : 109951.<\/a><br \/>\nDOI: 10.1016\/j.neuropharm.2024.109951<\/li>\n<li class=\"PubsList\"><a class=\"\" title=\"Microglial homeostasis disruption modulates non-rapid eye movement sleep duration and neuronal activity in adult female mice\" href=\"http:\/\/www.doi.org\/10.1016\/j.bbi.2022.09.016\" target=\"_blank\" rel=\"noopener\"> <span class=\"titrePub\">Microglial homeostasis disruption modulates non-rapid eye movement sleep duration and neuronal activity in adult female mice<\/span><br \/>\nKatherine Picard, Giorgio Corsi, Fanny Decoeur, Maria Amalia Di Castro, Maude Bordeleau, Marine Persillet, Sophie Lay\u00e9, Cristina Limatola, Marie-\u00c8ve Tremblay, <strong>Agn\u00e8s Nadjar<\/strong>.<br \/>\n<em> Brain, Behavior, and Immunity<\/em>. 2023-01-01. 107 : 153-164.<\/a><br \/>\nDOI: 10.1016\/j.bbi.2022.09.016<\/li>\n<li class=\"PubsList\"><a class=\"\" title=\"Microglia states and nomenclature: A field at its crossroads\" href=\"http:\/\/www.doi.org\/10.1016\/j.neuron.2022.10.020\" target=\"_blank\" rel=\"noopener\"> <span class=\"titrePub\">Microglia states and nomenclature: A field at its crossroads<\/span><br \/>\nRosa C. Paolicelli, Amanda Sierra, Beth Stevens, Marie-Eve Tremblay, (\u2026) <strong>Agnes Nadjar<\/strong>, (\u2026), Susanne A. Wolf, Long-Jun Wu, Tony Wyss-Coray.<br \/>\n<em> Neuron<\/em>. 2022-11-01. 110 (21) : 3458-3483.<\/a><br \/>\nDOI: 10.1016\/j.neuron.2022.10.020<\/li>\n<li class=\"PubsList\"><a class=\"\" title=\"N-3 PUFA Deficiency Affects the Ultrastructural Organization and Density of White Matter Microglia in the Developing Brain of Male Mice.\" href=\"http:\/\/www.doi.org\/10.3389\/fncel.2022.802411\" target=\"_blank\" rel=\"noopener\"> <span class=\"titrePub\">N-3 PUFA Deficiency Affects the Ultrastructural Organization and Density of White Matter Microglia in the Developing Brain of Male Mice.<\/span><br \/>\nFanny Decoeur, Katherine Picard, Marie-Kim St-Pierre, Andrew D. Greenhalgh, Jean-Christophe Delpech, Alexandra Sere, Sophie Lay\u00e9, Marie-Eve Tremblay, <strong>Agn\u00e8s Nadjar<\/strong>.<br \/>\n<em> Front. Cell. Neurosci.<\/em>. 2022-02-10. 16<br \/>\nDOI: 10.3389\/fncel.2022.802411<\/a><\/li>\n<li class=\"PubsList\"><a class=\"\" title=\"Microglial Cannabinoid Type 1 Receptor Regulates Brain Inflammation in a Sex-Specific Manner\" href=\"http:\/\/www.doi.org\/10.1089\/can.2020.0170\" target=\"_blank\" rel=\"noopener\"> <span class=\"titrePub\">Microglial Cannabinoid Type 1 Receptor Regulates Brain Inflammation in a Sex-Specific Manner<\/span><br \/>\nJulia De Meij, Zain Alfanek, Lydie Morel, Fanny Decoeur, Quentin Leyrolle, Katherine Picard, Micael Carrier, Agnes Aubert, Alexandra S\u00e9r\u00e9, C\u00e9line Lucas, Gerald Laforest, Jean-Christophe Helbling, Marie-Eve Tremblay, Daniela Cota, Marie-Pierre Moisan, Giovanni Marsicano, Sophie Lay\u00e9, <strong>Agn\u00e8s Nadjar<\/strong>.<br \/>\n<em> Cannabis and Cannabinoid Research<\/em>. 2021-12-01. 6 (6) : 488-507.<\/a><br \/>\nDOI: 10.1089\/can.2020.0170<\/li>\n<li class=\"PubsList\"><a class=\"\" title=\"N\u20103 PUFA deficiency disrupts oligodendrocyte maturation and myelin integrity during brain development\" href=\"http:\/\/www.doi.org\/10.1002\/glia.24088\" target=\"_blank\" rel=\"noopener\"> <span class=\"titrePub\">N\u20103 PUFA deficiency disrupts oligodendrocyte maturation and myelin integrity during brain development<\/span><br \/>\nQuentin Leyrolle, Fanny Decoeur, Cyril Dejean, Galadriel Bri\u00e8re, Stephane Leon, Ioannis Bakoyiannis, Emilie Baroux, Tony\u2010Lee Sterley, Cl\u00e9mentine Bosch\u2010Bouju, Lydie Morel, Camille Amadieu, Cynthia Lecours, Marie\u2010Kim St\u2010Pierre, Maude Bordeleau, V\u00e9ronique De Smedt\u2010Peyrusse, Alexandran S\u00e9r\u00e9, Leslie Schwendimann, Stephane Gr\u00e9goire, Lionel Bretillon, Niyazi Acar, Corinne Joffre, Guillaume Ferreira, Raluca Uricaru, Patricia Thebault, Pierre Gressens, Marie\u2010Eve Tremblay, Sophie Lay\u00e9, <strong>Agnes Nadjar<\/strong>.<br \/>\n<em> Glia<\/em>. 2021-09-14.<br \/>\nDOI: 10.1002\/glia.24088<\/a><\/li>\n<li class=\"PubsList\"><a class=\"\" title=\"Microglia\u2013Neuron Crosstalk in Obesity: Melodious Interaction or Kiss of Death?\" href=\"http:\/\/www.doi.org\/10.3390\/ijms22105243\" target=\"_blank\" rel=\"noopener\"> <span class=\"titrePub\">Microglia\u2013Neuron Crosstalk in Obesity: Melodious Interaction or Kiss of Death?<\/span><br \/>\nSt\u00e9phane L\u00e9on, <strong>Agn\u00e8s Nadjar<\/strong>, Carmelo Quarta.<br \/>\n<em> IJMS<\/em>. 2021-05-15. 22 (10) : 5243.<\/a><br \/>\nDOI: 10.3390\/ijms22105243<\/li>\n<li class=\"PubsList\"><a class=\"\" title=\"Essential omega-3 fatty acids tune microglial phagocytosis of synaptic elements in the mouse developing brain.\" href=\"http:\/\/www.doi.org\/10.1038\/s41467-020-19861-z\" target=\"_blank\" rel=\"noopener\"> <span class=\"titrePub\">Essential omega-3 fatty acids tune microglial phagocytosis of synaptic elements in the mouse developing brain.<\/span><br \/>\nC. Madore, Q. Leyrolle, L. Morel, M. Rossitto, A. D. Greenhalgh, J. C. Delpech, M. Martinat, C. Bosch-Bouju, J. Bourel, B. Rani, C. Lacabanne, A. Thomazeau, K. E. Hopperton, S. Beccari, A. Sere, A. Aubert, V. De Smedt-Peyrusse, C. Lecours, K. Bisht, L. Fourgeaud, S. Gregoire, L. Bretillon, N. Acar, N. J. Grant, J. Badaut, P. Gressens, A. Sierra, O. Butovsky, M. E. Tremblay, R. P. Bazinet, C. Joffre, <strong>A. Nadjar<\/strong>, S. Lay\u00e9.<br \/>\n<em> Nat Commun<\/em>. 2020-11-30. 11 (1)<br \/>\nDOI: 10.1038\/s41467-020-19861-z <\/a><\/li>\n<li class=\"PubsList\"><a class=\"\" title=\"Maternal dietary omega-3 deficiency worsens the deleterious effects of prenatal inflammation on the gut-brain axis in the offspring across lifetime\" href=\"http:\/\/www.doi.org\/10.1038\/s41386-020-00793-7\" target=\"_blank\" rel=\"noopener\"> <span class=\"titrePub\">Maternal dietary omega-3 deficiency worsens the deleterious effects of prenatal inflammation on the gut-brain axis in the offspring across lifetime<\/span><br \/>\nQ. Leyrolle, F. Decoeur, G. Briere, C. Amadieu, A. R. A. A. Quadros, I. Voytyuk, C. Lacabanne, A. Benmamar-Badel, J. Bourel, A. Aubert, A. Sere, F. Chain, L. Schwendimann, B. Matrot, T. Bourgeois, S. Gr\u00e9goire, J. G. Leblanc, A. De Moreno De Leblanc, P. Langella, G. R. Fernandes, L. Bretillon, C. Joffre, R. Uricaru, P. Thebault, P. Gressens, J. M. Chatel, S. Lay\u00e9, <strong>A. Nadjar.<\/strong><br \/>\n<em> Neuropsychopharmacol.<\/em>. 2020-08-11.<br \/>\nDOI: 10.1038\/s41386-020-00793-7<\/a><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Th\u00e9matique de recherche : communication entre le syst\u00e8me immunitaire et le syst\u00e8me nerveux central<\/p>\n","protected":false},"author":325,"featured_media":188981,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[737,321],"tags":[],"class_list":["post-189612","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-imn-en","category-interview"],"_links":{"self":[{"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/posts\/189612","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/users\/325"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/comments?post=189612"}],"version-history":[{"count":16,"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/posts\/189612\/revisions"}],"predecessor-version":[{"id":189672,"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/posts\/189612\/revisions\/189672"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/media\/188981"}],"wp:attachment":[{"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/media?parent=189612"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/categories?post=189612"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/tags?post=189612"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}