{"id":181552,"date":"2025-03-31T16:17:10","date_gmt":"2025-03-31T14:17:10","guid":{"rendered":"https:\/\/www.bordeaux-neurocampus.fr\/cajal-course-the-brain-prize-course-advanced-techniques-for-synapse-biology\/"},"modified":"2025-04-16T14:49:04","modified_gmt":"2025-04-16T12:49:04","slug":"cajal-course-the-brain-prize-course-advanced-techniques-for-synapse-biology","status":"publish","type":"post","link":"https:\/\/www.bordeaux-neurocampus.fr\/en\/cajal-course-the-brain-prize-course-advanced-techniques-for-synapse-biology\/","title":{"rendered":"Cajal course: “The Brain Prize Course: Advanced Techniques for Synapse Biology”"},"content":{"rendered":"

Venue: Bordeaux School of Neuroscience.<\/strong><\/p>\n

23 June – 11 July 2025<\/span><\/strong><\/p>\n

Registrations are open until 14 April<\/p>\n

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Course overview<\/b><\/h3>\n<\/div>\n<\/div>\n
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Synapses are sites of information transfer and storage in the brain. These specialised structures integrate complex signals and undergo functional changes that underlie the formation of memories. Synaptic dysfunction is associated with early stages of neurodegenerative disorders such as Alzheimer\u2019s disease, and underlies neurodevelopmental disorders such as autism spectrum disorders and intellectual disability.<\/p>\n

Studying\u00a0synapse function and plasticity\u00a0is key to understanding brain circuits that underlie behaviour, and to identify synaptic malfunction mechanisms underpinning brain diseases. This course will allow students to integrate theoretical and methodological concepts on\u00a0synapse biology\u00a0with hands-on experience on state-of-the art\u00a0imaging, functional and computational methodologies. The course provides an in-depth understanding to many concepts such as\u00a0synapse formation and maintenance, pre- and postsynaptic mechanisms, structural and functional synaptic plasticity, synaptic integration in neuronal networks and synaptopathies. Hands-on experimental projects conducted in small groups with the support of senior scientists will expose the students to methodologies at the forefront of research in this field.<\/p>\n

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Course Topics<\/b><\/h2>\n<\/div>\n<\/div>\n
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1. Activity-dependent regulation of gene expression and synapses<\/p>\n

2. Local protein synthesis and degradation<\/p>\n

3. Trafficking of synaptic proteins<\/p>\n

4. Synaptogenesis and synaptic plasticity<\/p>\n

5. Extracellular synaptic organizers, synaptic adhesion and circuit specification<\/p>\n

6. Synaptic integration in neuronal networks<\/p>\n

7. Presynaptic and postsynaptic mechanisms<\/p>\n

8. Excitation and inhibition<\/p>\n

9. Synaptic dysfunction in diseases<\/p>\n

10. Structure-function of synaptic proteins<\/p>\n

11. Neuromodulation<\/p>\n

12. Human-specific regulations of synapses<\/p>\n

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Course Directors<\/strong>
\n\u2013 C\u00e9cile Charrier \u2013 Institut de Biologie de l\u2019ENS, France
\n\u2013 Julien Dupuis \u2013 IINS \u2013 University of Bordeaux, France<\/p>\n

Honorary lectures from Brain Prize Winners: <\/strong>
\n\u2013 Erin Schuman \u2013 Max Planck Institute for Brain Research \u2013 Frankfurt, Germany
\n\u2013 Michael Greenberg \u2013 Harvard Medical School \u2013 Boston, USA<\/p>\n

Keynote Speakers:<\/strong>
\n\u2013 Corette Wierenga, Radboud Universiteit \u2013 Nijmegen, Netherlands
\n\u2013 Frank Polleux, Columbia University, New York, USA
\n\u2013 Monica Di Luca, Universit\u00e0 degli Studi di Milano, Italy
\n\u2013 Nelson Rebola, Institut du Cerveau, Paris, France
\n\u2013 Patrik Verstreken, VIB-KU Leuven Center for Brain & Disease Research, Belgium
\n\u2013 Peter Scheiffele, Universit\u00e4t Basel, Switzerland<\/p>\n

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More details about the course \/ registration<\/strong><\/a><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/section>\n","protected":false},"excerpt":{"rendered":"

23 June – 11 July 2025 – Deadline extension: Registrations are open until 14 April<\/p>\n","protected":false},"author":108,"featured_media":159354,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[86],"tags":[],"class_list":["post-181552","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-trainings"],"_links":{"self":[{"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/posts\/181552","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/users\/108"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/comments?post=181552"}],"version-history":[{"count":2,"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/posts\/181552\/revisions"}],"predecessor-version":[{"id":182326,"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/posts\/181552\/revisions\/182326"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/media\/159354"}],"wp:attachment":[{"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/media?parent=181552"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/categories?post=181552"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/tags?post=181552"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}