{"id":124111,"date":"2020-07-29T18:32:07","date_gmt":"2020-07-29T16:32:07","guid":{"rendered":"https:\/\/www.bordeaux-neurocampus.fr\/shauna-parkes-et-al-in-neurosci-biobehav-rev\/"},"modified":"2020-07-29T18:32:07","modified_gmt":"2020-07-29T16:32:07","slug":"shauna-parkes-et-al-in-neurosci-biobehav-rev","status":"publish","type":"post","link":"https:\/\/www.bordeaux-neurocampus.fr\/en\/shauna-parkes-et-al-in-neurosci-biobehav-rev\/","title":{"rendered":"Shauna Parkes et al in <em>Neurosci Biobehav Rev<\/em>"},"content":{"rendered":"<p>Everyday activities require adaptive decision-making and control over our actions to achieve our goals. Sub-regions within the cortex are widely reported to regulate these choices. In this review, we describe rodent studies from two disparate fields of instrumental action control \u2013 goal-directed and habitual responding, and impulsive and compulsive behaviour.<\/p>\n<p>Our aim was to compare findings across the spectrum, from precision associative learning to translational studies of action control. The evidence suggests that each cortical sub-region performs different roles depending on task requirements and, within tasks, clear dissociations exist between regions. Rather than synthesizing a single role or function for a given region, we should consider regions to be capable of many different functions. Further investigation of cortico-cortical connections and the pattern of input and output circuitry within each region may be needed to identify unique process-specific pathways.<\/p>\n<p>Overall, despite differences in the scope and purpose of these two fields, integrating evidence across tasks provides a broader context for testing hypotheses about the role of cortical regions in adaptive actions and decision-making.<\/p>\n<p><strong>Highlights:<\/strong><\/p>\n<ul>\n<li>Action control is measured by goal-directed learning and impulsive\/compulsive behavioural tasks<\/li>\n<li>Cortical regions have been implicated in various aspects of adaptive choice in both fields.<\/li>\n<li>These subregions have diverse, dissociable and shared roles.<\/li>\n<li>Comparing function across fields aids assessment of cortical regulation in the broader decision-making context.<\/li>\n<\/ul>\n<figure id=\"attachment_124104\" aria-describedby=\"caption-attachment-124104\" style=\"width: 374px\" class=\"wp-caption aligncenter\"><a href=\"https:\/\/www.bordeaux-neurocampus.fr\/wp-content\/uploads\/2020\/07\/Parkes-Figure-1_IBNS-1.jpg\" rel=\"lightbox[124111]\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-124104 \" src=\"https:\/\/www.bordeaux-neurocampus.fr\/wp-content\/uploads\/2020\/07\/Parkes-Figure-1_IBNS-1-545x770.jpg\" alt=\"Figure 1. An overview of behavioural paradigms commonly used to study action control in rodents. For a detailed explanation of these tasks see the full text at: https:\/\/doi.org\/10.1016\/j.neubiorev.2020.07.010\" width=\"374\" height=\"528\" \/><\/a><figcaption id=\"caption-attachment-124104\" class=\"wp-caption-text\">Figure 1. An overview of behavioural paradigms commonly used to study action control in rodents. For a detailed explanation of these tasks see the full text at: <a href=\"https:\/\/doi.org\/10.1016\/j.neubiorev.2020.07.010\">https:\/\/doi.org\/10.1016\/j.neubiorev.2020.07.010<\/a><\/figcaption><\/figure>\n<p>&nbsp;<\/p>\n<figure id=\"attachment_124102\" aria-describedby=\"caption-attachment-124102\" style=\"width: 484px\" class=\"wp-caption aligncenter\"><a href=\"https:\/\/www.bordeaux-neurocampus.fr\/wp-content\/uploads\/2020\/07\/Parkes-IBNS-Review_Figure-2_FINAL-1.jpg\" rel=\"lightbox[124111]\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-124102 \" src=\"https:\/\/www.bordeaux-neurocampus.fr\/wp-content\/uploads\/2020\/07\/Parkes-IBNS-Review_Figure-2_FINAL-1-770x661.jpg\" alt=\"Figure 2. Cortical regulation of actions. A graphical representation of the cortical regions involved in various cognitive and behavioural functions. For a detailed explanation of these functions and the tasks used to study them, see the full text: https:\/\/doi.org\/10.1016\/j.neubiorev.2020.07.010\" width=\"484\" height=\"415\" \/><\/a><figcaption id=\"caption-attachment-124102\" class=\"wp-caption-text\">Figure 2. Cortical regulation of actions. A graphical representation of the cortical regions involved in various cognitive and behavioural functions. For a detailed explanation of these functions and the tasks used to study them, see the full text: <a href=\"https:\/\/doi.org\/10.1016\/j.neubiorev.2020.07.010\">https:\/\/doi.org\/10.1016\/j.neubiorev.2020.07.010<\/a><\/figcaption><\/figure>\n<h3>Reference<\/h3>\n<p><em>Prefrontal regulation of behavioural control: Evidence from learning theory and translational approaches in rodents.<br \/>\n<\/em>Karly M Turner, <strong>Shauna L Parkes<\/strong><br \/>\n<em>Neurosci Biobehav Rev<\/em>. 2020 Jul 21;S0149-7634(20)30471-1.<br \/>\n<a href=\"https:\/\/doi.org\/10.1016\/j.neubiorev.2020.07.010\">10.1016\/j.neubiorev.2020.07.010<\/a><\/p>\n<h3>Contact<\/h3>\n<p><a href=\"https:\/\/www.bordeaux-neurocampus.fr\/staff\/shauna-parkes\/\"><strong>Shauna Parkes<\/strong><\/a><\/p>\n<p>Team: <a href=\"http:\/\/www.incia.u-bordeaux1.fr\/spip.php?article357\">Decision and Adaptation (INCIA)<\/a><\/p>\n<p><a class=\"mail-link\" title=\"shauna.parkes@u-bordeaux.fr\" href=\"mailto:shauna.parkes@u-bordeaux.fr\" data-enc-email=\"funhan.cnexrf[at]h-obeqrnhk.se\" data-wpel-link=\"ignore\">shauna.parkes@u-bordeaux.fr<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Prefrontal regulation of behavioural control: Evidence from learning theory and translational approaches in rodents.<\/p>\n","protected":false},"author":108,"featured_media":124107,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[71],"tags":[],"class_list":["post-124111","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-highlight-en"],"_links":{"self":[{"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/posts\/124111","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/users\/108"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/comments?post=124111"}],"version-history":[{"count":0,"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/posts\/124111\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/media\/124107"}],"wp:attachment":[{"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/media?parent=124111"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/categories?post=124111"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.bordeaux-neurocampus.fr\/en\/wp-json\/wp\/v2\/tags?post=124111"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}