{"version":"1.0","provider_name":"Bordeaux Neurocampus","provider_url":"https:\/\/www.bordeaux-neurocampus.fr\/en\/","author_name":"Bordeaux Neurocampus","author_url":"https:\/\/www.bordeaux-neurocampus.fr\/en\/","title":"Hereditary spastic paraplegias: an update. - Bordeaux Neurocampus","type":"rich","width":600,"height":338,"html":"<blockquote class=\"wp-embedded-content\" data-secret=\"XAPrJHGfwy\"><a href=\"https:\/\/www.bordeaux-neurocampus.fr\/en\/article\/hereditary-spastic-paraplegias-an-update\/\">Hereditary spastic paraplegias: an update.<\/a><\/blockquote><iframe sandbox=\"allow-scripts\" security=\"restricted\" src=\"https:\/\/www.bordeaux-neurocampus.fr\/en\/article\/hereditary-spastic-paraplegias-an-update\/embed\/#?secret=XAPrJHGfwy\" width=\"600\" height=\"338\" title=\"&#8220;Hereditary spastic paraplegias: an update.&#8221; &#8212; Bordeaux Neurocampus\" data-secret=\"XAPrJHGfwy\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\" class=\"wp-embedded-content\"><\/iframe><script>\n\/*! This file is auto-generated *\/\n!function(d,l){\"use strict\";l.querySelector&&d.addEventListener&&\"undefined\"!=typeof URL&&(d.wp=d.wp||{},d.wp.receiveEmbedMessage||(d.wp.receiveEmbedMessage=function(e){var t=e.data;if((t||t.secret||t.message||t.value)&&!\/[^a-zA-Z0-9]\/.test(t.secret)){for(var s,r,n,a=l.querySelectorAll('iframe[data-secret=\"'+t.secret+'\"]'),o=l.querySelectorAll('blockquote[data-secret=\"'+t.secret+'\"]'),c=new RegExp(\"^https?:$\",\"i\"),i=0;i<o.length;i++)o[i].style.display=\"none\";for(i=0;i<a.length;i++)s=a[i],e.source===s.contentWindow&&(s.removeAttribute(\"style\"),\"height\"===t.message?(1e3<(r=parseInt(t.value,10))?r=1e3:~~r<200&&(r=200),s.height=r):\"link\"===t.message&&(r=new URL(s.getAttribute(\"src\")),n=new URL(t.value),c.test(n.protocol))&&n.host===r.host&&l.activeElement===s&&(d.top.location.href=t.value))}},d.addEventListener(\"message\",d.wp.receiveEmbedMessage,!1),l.addEventListener(\"DOMContentLoaded\",function(){for(var e,t,s=l.querySelectorAll(\"iframe.wp-embedded-content\"),r=0;r<s.length;r++)(t=(e=s[r]).getAttribute(\"data-secret\"))||(t=Math.random().toString(36).substring(2,12),e.src+=\"#?secret=\"+t,e.setAttribute(\"data-secret\",t)),e.contentWindow.postMessage({message:\"ready\",secret:t},\"*\")},!1)))}(window,document);\n\/\/# sourceURL=https:\/\/www.bordeaux-neurocampus.fr\/wp-includes\/js\/wp-embed.min.js\n<\/script>\n","description":"1. Curr Opin Neurol. 2007 Dec;20(6):674-80. Hereditary spastic paraplegias: an update. Depienne C(1), Stevanin G, Brice A, Durr A. Author information: (1)INSERM, U679, Paris, France. PURPOSE OF REVIEW: Hereditary spastic paraplegias are a genetically heterogeneous group of diseases. Recent advances concerning their nosology and molecular bases have greatly improved the genetic diagnosis of these diseases, with implications for genetic counselling. The recent identification of new genes and loci, however, has blurred the distinction between hereditary spastic paraplegias and other entities, such as cerebellar ataxias or leucodystrophies. Cerebral MRI and the familial history of each patient with spastic paraplegia are the&hellip;"}