1.0Bordeaux Neurocampushttps://www.bordeaux-neurocampus.fr/en/didierLeRayhttps://www.bordeaux-neurocampus.fr/en/author/didierleray/rich600338<blockquote class="wp-embedded-content" data-secret="h5HHMVqPOt"><a href="https://www.bordeaux-neurocampus.fr/en/team/motopsyn/">Motoneurons and synaptic partners (MotoPSyn)</a></blockquote><iframe sandbox="allow-scripts" security="restricted" src="https://www.bordeaux-neurocampus.fr/en/team/motopsyn/embed/#?secret=h5HHMVqPOt" width="600" height="338" title="“Motoneurons and synaptic partners (MotoPSyn)” — Bordeaux Neurocampus" data-secret="h5HHMVqPOt" frameborder="0" marginwidth="0" marginheight="0" scrolling="no" class="wp-embedded-content"></iframe><script type="text/javascript"> /* <![CDATA[ */ /*! This file is auto-generated */ !function(d,l){"use strict";l.querySelector&&d.addEventListener&&"undefined"!=typeof URL&&(d.wp=d.wp||{},d.wp.receiveEmbedMessage||(d.wp.receiveEmbedMessage=function(e){var t=e.data;if((t||t.secret||t.message||t.value)&&!/[^a-zA-Z0-9]/.test(t.secret)){for(var s,r,n,a=l.querySelectorAll('iframe[data-secret="'+t.secret+'"]'),o=l.querySelectorAll('blockquote[data-secret="'+t.secret+'"]'),c=new RegExp("^https?:$","i"),i=0;i<o.length;i++)o[i].style.display="none";for(i=0;i<a.length;i++)s=a[i],e.source===s.contentWindow&&(s.removeAttribute("style"),"height"===t.message?(1e3<(r=parseInt(t.value,10))?r=1e3:~~r<200&&(r=200),s.height=r):"link"===t.message&&(r=new URL(s.getAttribute("src")),n=new URL(t.value),c.test(n.protocol))&&n.host===r.host&&l.activeElement===s&&(d.top.location.href=t.value))}},d.addEventListener("message",d.wp.receiveEmbedMessage,!1),l.addEventListener("DOMContentLoaded",function(){for(var e,t,s=l.querySelectorAll("iframe.wp-embedded-content"),r=0;r<s.length;r++)(t=(e=s[r]).getAttribute("data-secret"))||(t=Math.random().toString(36).substring(2,12),e.src+="#?secret="+t,e.setAttribute("data-secret",t)),e.contentWindow.postMessage({message:"ready",secret:t},"*")},!1)))}(window,document); //# sourceURL=https://cdn-neurocampus.onlc.eu/wp-includes/js/wp-embed.min.js /* ]]> */ </script> https://cdn-neurocampus.onlc.eu/wp-content/uploads/2018/06/branchereau-le-ray-pp-DSC_5688.jpg800600The objective of our team is to understand the mechanisms involved in the function of mammal spinal motor networks from its embryonic development to its pathological conditions, such as amyotrophic lateral sclerosis, ALS. In particular, we focus our efforts on: 1) deciphering the role of GABAergic interneuron in the genesis of spontaneous activity at early developmental stages and 2) identifying cellular and molecular mechanisms involved in the early motor deficits observed in spinal motoneurons from ALS mouse models. Innovative techniques | electrophysiology in vitro, ALS mouse models