Du 4 septembre 2017 au 22 septembre 2017
Cajal school 2017 / Bordeaux Neurocampus
Ion channels play a major role in neuronal excitability. Diseases, termed channelopathies, are related to inherited or acquired dysfunctions of ion channels: epilepsy, migraine, ataxia and deafness. Roughly 15% of known therapeutic drugs including anaesthetics, analgesics, anti-epileptics and anxiolytics have their primary action on ion channels, making them the second largest target class after G-protein coupled receptors. With the advent of a better understanding of cellular physiology and identification of the molecular components that constitute individual channel types and/or control their activity, rational molecular-based strategies to identify ion channel modulators are now within reach.
We are organizing a summer course to provide promising young investigators with a comprehensive introduction to state-of-the-art techniques in ion channel study, including – but not limited – to genetics, electrophysiology, imaging, as well as structure-function and pathophysiological approaches. This 3-week course is a practical “hands-on” introduction to advanced methods in ion channel recording and analysis and will cover sufficient background such that all participants will be able to establish these techniques in their home laboratories.